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Key Documents

M8005

Sigma-Aldrich

Sodium myristate

≥99%

Synonyma:

Myristic acid sodium salt, Tetradecanoic acid sodium salt

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About This Item

Lineární vzorec:
CH3(CH2)12COONa
Číslo CAS:
Molekulová hmotnost:
250.35
Beilstein/REAXYS Number:
3575157
EC Number:
MDL number:
UNSPSC Code:
12352211
PubChem Substance ID:
NACRES:
NA.25

biological source

plant (vegetable)

assay

≥99%

form

powder

functional group

ester

lipid type

saturated FAs

shipped in

ambient

storage temp.

2-8°C

SMILES string

[Na+].CCCCCCCCCCCCCC([O-])=O

InChI

1S/C14H28O2.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14(15)16;/h2-13H2,1H3,(H,15,16);/q;+1/p-1

InChI key

JUQGWKYSEXPRGL-UHFFFAOYSA-M

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Biochem/physiol Actions

Myristate (tetradecanoic acid) is a saturated (C14:0) medium-chain fatty acid. Sodium myristate is used in surfactant, cholloidal and hydrophobic/absorption chemistry involving molecules such as proteins.
Myristic acid is commonly added via a covalent linkage to the N-terminal glycine of many eukaryotic and viral proteins, a process called myristoylation. Myristoylation enables proteins to bind to cell membranes and facilitates protein-protein interactions. Myristolyation of proteins affect many cellular functions and thus has implications in health and disease .

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Osvědčení o analýze (COA)

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Fibrinogen (FB), a serum protein, is considered a major inhibitor of lung surfactant function at the lining layer of the alveoli. In this study, the adsorption of aqueous bovine FB at the air/water interface was investigated with tensiometry and directly
Wen et al.
Journal of colloid and interface science, 231(1), 42-51 (2000-11-18)
Aqueous sodium myristate solutions have been shown to have unusually low dynamic tensions (1-10 mN/m) under pulsating area conditions. These solutions have no sharp solubility limit, evidently because they are protonated (or "hydrolyzed") to form the much less soluble myristic
Scott J McClellan et al.
Langmuir : the ACS journal of surfaces and colloids, 21(22), 10148-10153 (2005-10-19)
The competitive adsorption of proteins and surfactants has applications to chromatographic systems and biological materials. Adsorption for systems of bovine serum albumin (BSA) and sodium myristate (SM) was investigated with in-situ ATR-IR spectroscopy and ex-situ ellipsometry. The results were used
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