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Lidocaine

Name: Lidocaine
Brand: SIGMA
Price: 148 USD
Availability: InStock

Na+ channel blocker, solid

Synonym(s):

2-Diethylamino-N-(2,6-dimethylphenyl)acetamide, Lignocaine, Xylocaine

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Size/SKU	Availability	Price
1 vial	Check Cart for Availability	$148.00

About This Item

Empirical Formula (Hill Notation):

C₁₄H₂₂N₂O

CAS Number:

137-58-6

Molecular Weight:

234.34

NACRES:

NA.77

PubChem Substance ID:

24896272

UNSPSC Code:

12352200

EC Number:

205-302-8

MDL number:

MFCD00026733

Form:

solid

$148.00

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Properties

Product Name

Lidocaine, analytical standard

grade

analytical standard

Quality Segment

200

form

solid

packaging

vial of 200 mg

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

impurities

≤0.5% Total Organic Impurities (Lidocaine related compound H ≤0.10%

2,6-Dimethylaniline ≤0.01%

Any unspecified impurity ≤0.10%

Total impurities ≤0.5%)

application(s)

forensics and toxicology
pharmaceutical (small molecule)

SMILES string

CCN(CC)CC(=O)Nc1c(C)cccc1C

InChI

1S/C14H22N2O/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4/h7-9H,5-6,10H2,1-4H3,(H,15,17)

InChI key

NNJVILVZKWQKPM-UHFFFAOYSA-N

Gene Information

human ... CYP1A2(1544), SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)
rat ... Scnn1a(25122)

Description

General description

Lidocaine is an amide anesthetic, which is used to treat ventricular arrhythmias. It lowers cardiac automaticity and myocardial conduction. Lidocaine inhibits the generation and conduction of nerve impulses. It has an anticonvulsant effect.

Application

Lidocaine has been used to examine its effects in inhibiting lymph flow and protection against envenomation. It has also been used to assess its efficacy as an anti-tussive agent.

Biochem/physiol Actions

Na⁺ channel blocker; class IB antiarrhythmic that is rapidly absorbed after parenteral administration.

Na⁺ channel blocker; class IB antiarrhythmic.

Packaging

Supplied in amber screw-cap vials

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1 of 1

This Item	L7757	PHR1034	L0595000
Sigma-Aldrich L1026 Lidocaine	Sigma-Aldrich L7757 Lidocaine	Supelco PHR1034 Lidocaine	L0595000 Lidocaine
form solid	form powder	form -	form -
technique(s) HPLC: suitable, gas chromatography (GC): suitable	technique(s) -	technique(s) HPLC: suitable, gas chromatography (GC): suitable	technique(s) HPLC: suitable, gas chromatography (GC): suitable
Quality Level 200	Quality Level 100	Quality Level 300	Quality Level -
application(s) forensics and toxicology pharmaceutical (small molecule)	application(s) -	application(s) cleaning products cosmetics food and beverages personal care pharmaceutical (small molecule)	application(s) pharmaceutical (small molecule)
impurities ≤0.5% Total Organic Impurities (Lidocaine related compound H ≤0.10% 2,6-Dimethylaniline ≤0.01% Any unspecified impurity ≤0.10% Total impurities ≤0.5%)	impurities -	impurities -	impurities -
grade analytical standard	grade -	grade certified reference material, pharmaceutical secondary standard	grade pharmaceutical primary standard

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pictograms

GHS07

signalword

Warning

hcodes

H302

pcodes

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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