B7652

Betamethasone 21-phosphate disodium

≥97%

• Synonyma: Betamethasone disodium phosphate, Betamethasone sodium phosphate
• Empirický vzorec (Hillův zápis): C₂₂H₂₈FNa₂O₈P
• Číslo CAS: 151-73-5
• Molekulová hmotnost: 516.40
• EC Number: 205-797-0
• MDL number: MFCD00200361
• UNSPSC Code: 12352200
• PubChem Substance ID: 24892013
• NACRES: NA.77

Vlastnosti

• sterility: non-sterile
• assay: ≥97%
• form: powder
• solubility: water: 50 mg/mL, clear to very slightly hazy, faintly yellow
• shipped in: ambient
• storage temp.: room temp
• SMILES string: [Na+].[Na+].[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1(F)[C@@H](O)C[C@@]4(C)[C@@]2([H])C[C@H](C)[C@]4(O)C(=O)COP([O-])([O-])=O
• InChI: 1S/C22H30FO8P.2Na/c1-12-8-16-15-5-4-13-9-14(24)6-7-19(13,2)21(15,23)17(25)10-20(16,3)22(12,27)18(26)11-31-32(28,29)30;;/h6-7,9,12,15-17,25,27H,4-5,8,10-11H2,1-3H3,(H2,28,29,30);;/q;2*+1/p-2/t12-,15-,16-,17-,19-,20-,21-,22-;;/m0../s1
• InChI key: PLCQGRYPOISRTQ-LWCNAHDDSA-L
• Gene Information: human ... NR3C1(2908)

Popis

Biochem/physiol Actions

Betamethasone is used to treat neonatal respiratory distress syndrome, and psoriasis.

Diagnostic Implications

Betamethasone is a corticosteroid with anti-inflammatory and immunosuppressive abilities, used especially where water retention is undesirable. It is applied as a topical cream, ointment, lotion or gel to treat itching (e.g. from eczema). Corticosteroid used to stimulate fetal lung maturation and to decrease the incidence and mortality from intracranial hemorrhage in premature infants

Bezpečnostní informace

• pictograms: GHS08,GHS07
• signalword: Danger
• hcodes: H302,H360FD,H373
• pcodes: P202 - P260 - P264 - P280 - P301 + P312 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Repr. 1B - STOT RE 2
• target_organs: Liver,Kidney,Endocrine system
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3
• ppe: dust mask type N95 (US), Eyeshields, Gloves