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A9920

Sigma-Aldrich

β-Alanine

BioReagent, suitable for cell culture, suitable for insect cell culture

Synonyma:

β-Ala, 3-Aminopropionic acid

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About This Item

Lineární vzorec:
NH2CH2CH2COOH
Číslo CAS:
107-95-9
Molekulová hmotnost:
89.09
Beilstein/REAXYS Number:
906793
EC Number:
203-536-5
MDL number:
MFCD00008200
UNSPSC Code:
12352209
eCl@ss:
39030936
PubChem Substance ID:
24891409
NACRES:
NA.75

product line

BioReagent

assay

≥98% (TLC)

form

powder or crystals

technique(s)

cell culture | insect: suitable
cell culture | mammalian: suitable

color

white

mp

202 °C (dec.) (lit.)

SMILES string

NCCC(O)=O

InChI

1S/C3H7NO2/c4-2-1-3(5)6/h1-2,4H2,(H,5,6)

InChI key

UCMIRNVEIXFBKS-UHFFFAOYSA-N

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General description

An N-blocked form of alanine.

Biochem/physiol Actions

β-Alanine, a β−amino acid, is a component of pantothenic acid and the rate-limiting amino acid in the biosynthesis of the histidinyl antioxidant dipeptides carnosine and anserine. Endogenous β-amino acid that is a nonselective agonist at glycine receptors and a ligand for the G protein-coupled orphan receptor, TGR7 (MrgD). β-Alanine flux plays a cytoprotective role by supporting the osmotic stability of marine organisms, preimplantation mouse embryos and mammalian cells exposed to hypoxic stress.

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Osvědčení o analýze (COA)

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Robert G Hart et al.
The Canadian journal of cardiology, 29(7 Suppl), S71-S78 (2013-06-29)
Chronic kidney disease (CKD) is prevalent in elderly patients with atrial fibrillation and is an independent risk factor for stroke. Warfarin anticoagulation is efficacious for stroke prevention in atrial fibrillation patients with moderate CKD (stage III, estimated glomerular filtration rate
Ammar Majeed et al.
Circulation, 128(21), 2325-2332 (2013-10-02)
The aim of this study was to compare the management and prognosis of major bleeding in patients treated with dabigatran or warfarin. Two independent investigators reviewed bleeding reports from 1034 individuals with 1121 major bleeds enrolled in 5 phase III
Ramin Artang et al.
The American journal of cardiology, 112(12), 1973-1979 (2013-10-01)
Dabigatran has been associated with greater risk of myocardial infarction (MI) than warfarin. It is unknown whether the increased risk is unique to dabigatran, an adverse effect shared by other oral direct thrombin inhibitors (DTIs), or the result of a
K M Gibson et al.
Journal of neurochemistry, 81(1), 71-79 (2002-06-18)
Metabolite profiling in succinate semialdehyde dehydrogenase (SSADH; Aldh5a1-/-) deficient mice previously revealed elevated gamma-hydroxybutyrate (GHB) and total GABA in urine and total brain and liver extracts. In this study, we extend our metabolic characterization of these mutant mice by documenting
Wilma Potze et al.
British journal of haematology, 163(5), 666-673 (2013-11-14)
There is increasing recognition that thrombotic complications may occur in patients with cirrhosis, and literature on antithrombotic treatment in these patients is rapidly emerging. Due to extensive haemostatic changes in patients with cirrhosis, careful monitoring of anticoagulant therapy may be
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Sortimentní položky

β-Alanine in Cell Culture

Learn more about β-Alanine, an important amino acid supplement and explore how it is used in cell culture. We offer a comprehensive portfolio of amino acid cell culture supplements and reagents.

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