Přejít k obsahu
Merck

Přeskočit na

A5960

L-Ascorbic acid

BioXtra, ≥99.0%, crystalline

Synonyma:

L-Threoascorbic acid, Antiscorbutic factor, Vitamin C

Přihlásit pro zobrazení organizačních a smluvních cen.

Vybrat velikost

Změnit zobrazení
Velikost baleníSkladová položkaDostupnostCena
10 mg
Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti.
865,00 Kč
25 g
Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti.
2 260,00 Kč
100 g
Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti.
7 190,00 Kč
500 g
Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti.
19 300,00 Kč

O této položce

Empirický vzorec (Hillův zápis):
C6H8O6
Číslo CAS:
Molekulová hmotnost:
176.12
UNSPSC Code:
12352209
NACRES:
NA.26
PubChem Substance ID:
EC Number:
200-066-2
Beilstein/REAXYS Number:
84272
MDL number:

865,00 Kč


Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti.

Požádejte o hromadnou objednávku
Technický servis
Potřebujete pomoc? Náš tým zkušených odborníků je vám k dispozici.
Dovolte nám, abychom vám pomohli


product line

BioXtra

Quality Segment

assay

≥99.0%

form

crystalline

technique(s)

cell culture | mammalian: suitable

impurities

≤0.0005% Phosphorus (P), ≤0.1% Insoluble matter

ign. residue

≤0.1%

color

white to off-white

pH

1.0-2.5 (25 °C, 176 g/L in water)

mp

190-194 °C (dec.)

solubility

H2O: 0.5 M, clear, colorless

anion traces

sulfate (SO42-): ≤0.05%

cation traces

Al: ≤0.0005%, Ca: ≤0.0005%, Cu: ≤0.0005%, Fe: ≤0.0005%, K: ≤0.005%, Mg: ≤0.0005%, NH4+: ≤0.05%, Na: ≤0.005%, Pb: ≤0.001%, Zn: ≤0.0005%

SMILES string

OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O

InChI

1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1

InChI key

CIWBSHSKHKDKBQ-JLAZNSOCSA-N

Gene Information

human ... SLC23A2(9962)

General description

Ascorbic acid is also referred to as Vitamin C. It contains a six-carbon lactone produced by plants and some animal species but not by humans and other primates. Vitamin C is a water-soluble vitamin. Vitamin C is a part of citrus fruits, such as Indian gooseberry, broccoli, strawberries, brussels sprouts. L-ascorbic acid is the biologically active form of ascorbic acid. It is unstable and hydrophilic. Ascorbic acid carries a neutral charge, which gets converted to ascorbate by protonation.

Application

  • L-Ascorbic acid has been used to induce osteoblast differentiation from primary bone marrow cultures.[1]
  • It has been used for the differentiation of hCMPCs (human cardiomyocyte progenitor cells) into cardiomyocytes.[2]
  • It has been used to measure the mitochondrial electron transport chain (complex IV) activity.

Biochem/physiol Actions

L-Ascorbic acid plays a role in production of neurotransmitters, carnitine and collagen synthesis. Ascorbic acid functions as an enzymatic cofactor for multiple enzymes, serving as an electron donor for monooxygenases and dioxygenases. Ascorbic acid also functions as a powerful antioxidant, particularly in regards to reactive oxygen species. Vitamin C exhibits anti-oxidant properties. Vitamin C is implicated in conferring protection against photoaging and anti-aging. Deficiency of vitamin C is associated with scurvy, bleeding gums, poor wound healing, anemia and muscle degeneration.

Disclaimer

May darken in storage.

Porovnat podobné položky

Zobrazit úplné porovnání

Zobrazit rozdíly

1 of 1

Tato položka
95209A750633034
technique(s)

cell culture | mammalian: suitable

technique(s)

-

technique(s)

HPLC: suitable, cell culture | stem cell: suitable

technique(s)

IR spectroscopy: suitable

assay

≥99.0%

assay

≥99.5% (RT)

assay

≥98% ( with iodine, titration)

assay

99.7-100.5% (oxidimetric)

form

crystalline

form

powder or crystals

form

crystalline

form

solid

solubility

H2O: 0.5 M, clear, colorless

solubility

H2O: 1 M at 20 °C, clear, colorless

solubility

water: soluble 50 mg/mL

solubility

water: soluble 176 g/L at 20 °C

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

cation traces

Al: ≤0.0005%, Cu: ≤0.0005%, K: ≤0.005%, NH4+: ≤0.05%, Pb: ≤0.001%, Ca: ≤0.0005%, Mg: ≤0.0005%, Zn: ≤0.0005%, Fe: ≤0.0005%, Na: ≤0.005%

cation traces

Al: ≤5 mg/kg, As: ≤0.1 mg/kg, Ba: ≤5 mg/kg, Bi: ≤5 mg/kg, Ca: ≤25 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤50 mg/kg, Li: ≤5 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Mo: ≤5 mg/kg, Na: ≤50 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Sr: ≤5 mg/kg, Zn: ≤5 mg/kg

cation traces

-

cation traces

As: ≤1 mg/kg, Cu: ≤5 mg/kg, Fe: ≤2 mg/kg, Pb: ≤5 mg/kg, Zn: ≤10 mg/kg


Still not finding the right product?

Explore all of our products under L-Ascorbic acid


Skladovací třída

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



Vyberte jednu z posledních verzí:

Osvědčení o analýze (COA)

Lot/Batch Number

Nevidíte správnou verzi?

Potřebujete-li konkrétní verzi, můžete vyhledat daný certifikát podle čísla dávky nebo čísla šarže.

Již tento produkt vlastníte?

Dokumenty související s produkty, které jste v minulosti zakoupili, byly za účelem usnadnění shromážděny ve vaší Knihovně dokumentů.

Navštívit knihovnu dokumentů


Sortimentní položky

Single molecule electronics is the endeavour of constructing electronic circuitry with single molecules as the fundamental building block.






Globální číslo obchodní položky

Skladová položkaGTIN
A5960-10MG04061835542291
A5960-25G04061835521548
A5960-500G04061835542307
A5960-100G04061835542284

Questions

1–7 of 7 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. Is L-ascorbic acid, Product A5960, the same as vitamin C?

    1 answer
    1. Yes, L-ascorbic acid is a synonym for vitamin C.

      Helpful?

  4. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

  5. What is the pKa of L-ascorbic acid, Product A5960?

    1 answer
    1. The pKa values for L-ascorbic acid (from the chemicals encyclopedia published by the Royal Society of Chemistry) are 4.17 and 11.57.

      Helpful?

  6. What is the extinction coefficient of L-ascorbic acid, Product A5960?

    1 answer
    1. According to the Data for Biochemical Research, 3rd ed., Dawson, R. M. C., et al., Oxford University Press (New York, NY 1986), p. 116, the L-ascorbic acid extinction coefficient: EmM = 7.0 (265 nm, water), 7.5 (245 nm, acid).

      Helpful?

  7. What is the solution stability of L-ascorbic acid, Product A5960?

    1 answer
    1. Aqueous solutions are stable only in the absence of oxygen.  Aqueous solutions are most stable at pH 5-6, very unstable at alkaline pH. (Data for Biochemical Research, 3rd ed., Dawson, R. M. C., et al., Oxford University Press (New York, NY: 1986), p. 116)  Degradation is markedly increased in the presence of transition metal ions, especially Cu(II) and Fe(III).  The first stage of oxidation of L-ascorbic acid to dehydroascorbic acid is reversible and the biological activity is retained.  Further oxidation to 2,3-diketogulonic acid is not reversible and the activity is lost. (Omura, H., and Yamafuji, K., in Methodicum Chimicum, 11(2), Korte, F., and Goto, M., eds., Academic Press (New York, NY: 1977), p. 115).

      Helpful?

Reviews

No rating value

Active Filters