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238422

2-Bromohexadecanoic acid

~97%, PPARδ agonist, solid

Synonym(s):

2-Bromopalmitic acid

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Size/SKUAvailabilityPrice
10 g

Available to ship TODAYfromMILWAUKEE

$56.60
50 g

Available to ship TODAYfromMILWAUKEE

$218.00

About This Item

Linear Formula:
CH3(CH2)13CH(Br)CO2H
CAS Number:
Molecular Weight:
335.32
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352203
EC Number:
242-137-0
MDL number:
Beilstein/REAXYS Number:
1726517
Assay:
~97%
Form:
solid

$56.60


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Product Name

2-Bromohexadecanoic acid, ~97%

assay

~97%

Quality Segment

form

solid

SMILES string

CCCCCCCCCCCCCCC(Br)C(O)=O

InChI

1S/C16H31BrO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15(17)16(18)19/h15H,2-14H2,1H3,(H,18,19)

InChI key

DPRAYRYQQAXQPE-UHFFFAOYSA-N

Gene Information

human ... PPARD(5467)

General description

PPARδ (peroxisome proliferator-activated receptor, delta isoform) acts as a transcription factor for gene expression as well as playing a role in lipid metabolism regulation; activity of this receptor is ligand-regulated. 2-Bromohexadecanoic acid is a metabolically stable analoge of the fatty acid palmitic acid that has been shown to be a natural ligand for the PPARδ receptor.[1] 2-Bromohexadecanoic acid has also been used in studies of fatty acid oxidation, palmitoylation, and glucose uptake.

Biochem/physiol Actions

2-Bromohexadecanoic acid is a PPARδ agonist. It has also been shown to inhibit fatty acid oxidation, inhibit DHHC-mediated palmitoylation[2], and promote glucose uptake in rat cardiac cells and the insulin-sensitive murine fibroblast line A31-IS[3].

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This Item
2160476169676380
form

solid

form

solid

form

-

form

solid

assay

~97%

assay

≥99.0% (GC)

assay

≥98.5% (GC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

200

Quality Level

100

Quality Level

100

Gene Information

human ... PPARD(5467)

Gene Information

human ... PPARD(5467)

Gene Information

-

Gene Information

-


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

235.4 °F - closed cup

flash_point_c

113 °C - closed cup

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Questions

  1. Does the solution need to be stored away from light?

    1 answer
    1. There is no indication that this product is light sensitive in solution. It is recommended that solutions be stored in aliquots at - 20 deg C for up to 1 month. Keep containers tightly sealed. Avoid repeated freeze/thaw cycles.

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