PHL89700

Harmaline

phyproof^® Reference Substance

• Synonyma: 1-Methyl-7-methoxy-3,4-dihydro-β-carboline, 3,4-Dihydroharmine, 4,9-Dihydro-7-methoxy-1-methyl-3H-pyrido[3,4-b]indole, Dihydroharmine, Harmalol methyl ether, Harmidine, NSC 407285
• Empirický vzorec (Hillův zápis): C₁₃H₁₄N₂O
• Číslo CAS: 304-21-2
• Molekulová hmotnost: 214.26
• Beilstein/REAXYS Number: 207310
• MDL number: MFCD00004955
• UNSPSC Code: 41116107
• NACRES: NA.24

Vlastnosti

• grade: primary reference standard
• product line: phyproof^® Reference Substance
• assay: ≥95.0% (HPLC)
• manufacturer/tradename: PhytoLab
• drug control: stupéfiant (France); regulated under CDSA - not available from Sigma-Aldrich Canada
• mp: 232-234 °C (lit.)
• application(s): food and beverages
• format: neat
• SMILES string: COc1ccc2c3CCN=C(C)c3[nH]c2c1
• InChI: 1S/C13H14N2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13/h3-4,7,15H,5-6H2,1-2H3
• InChI key: RERZNCLIYCABFS-UHFFFAOYSA-N

Popis

General description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Application

Reactant for preparation of:

• Acylated harmalines via Friedel-Crafts reaction
• Phenacyl derivatives of 1-methyl-7-methoxy-β-carbolines as central nervous system affectors
• Palladium harmaline DMSO chloro complex as anti-tumor agent

Natural product scaffold in preparation of:

• Trypanothione reductase inhibitors†

Biochem/physiol Actions

CNS stimulant; may act through NMDA receptors

Legal Information

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

Bezpečnostní informace

• pictograms: GHS08,GHS07
• signalword: Warning
• hcodes: H302,H371
• pcodes: P260 - P264 - P301 + P312 - P308 + P311 - P405 - P501
• Hazard Classifications: Acute Tox. 4 Oral - STOT SE 2
• target_organs: Central nervous system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable