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M1511

Sodium 2-mercaptoethanesulfonate

analytical standard, ≥98.0% (titration)

Synonyma:

2-Mercaptoethanesulfonic acid sodium salt, Coenzyme M sodium salt, HS-CoM Na, MESNA

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Vám/Skladová položkaDostupnostCena
5 g
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1 880,00 Kč
10 g
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3 300,00 Kč
25 g
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6 810,00 Kč

O této položce

Lineární vzorec:
HSCH2CH2SO3Na
Číslo CAS:
Molekulová hmotnost:
164.18
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
243-285-9
Beilstein/REAXYS Number:
3657828
MDL number:

1 880,00 Kč


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grade

analytical standard

Quality Segment

assay

≥98.0% (titration)

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

SMILES string

[Na+].[O-]S(=O)(=O)CCS

InChI

1S/C2H6O3S2.Na/c3-7(4,5)2-1-6;/h6H,1-2H2,(H,3,4,5);/q;+1/p-1

InChI key

XOGTZOOQQBDUSI-UHFFFAOYSA-M

General description

Sodium 2-mercaptoethanesulfonate is a thiol compound commonly used as an auxiliary drug, to reduce the side effects of anti-cancer drugs, such as oxazaphosphorine, cyclophosphamide, and ifosfamide. It acts by forming a non-toxic compound upon reacting with the toxic metabolites of the drugs like acrolein.

Application

The analytical standard can also be used as follows:
  • Quantification of sodium 2-mercaptoethanesulfonate (MESNA) from human samples by micellar electrokinetic chromatography (MEKC) coupled with UV detection and in-capillary derivatization of MESNA
  • Development of a fluorescence-enhanced histidine stabilized gold nanoclusters (His-Au NCs) based probe for the detection of sodium 2-mercaptoethanesulfonate in uromitexan samples
  • High-performance liquid chromatography-tandem mass spectrometric based bioanalysis of sodium 2-mercaptoethanesulfonate in rat plasma samples
  • To quantify sodium 2-mercaptoethanesulfonate in two of its pharmaceutical preparations (injections) by surface-enhanced Raman scattering (SERS) using gold colloid as a probe

Other Notes

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Porovnat podobné položky

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Tato položka
637058.10595PHR1570
Mesna Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1570

Mesna

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

-

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

format

neat

format

-

format

-

format

neat

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

300

grade

analytical standard

grade

-

grade

-

grade

certified reference material, pharmaceutical secondary standard

assay

≥98.0% (titration)

assay

≥98.0% (RT)

assay

-

assay

-

application(s)

clinical testing

application(s)

-

application(s)

-

application(s)

pharmaceutical (small molecule)


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pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Skladovací třída

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Osvědčení o analýze (COA)

Lot/Batch Number

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Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

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