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90984

Supelco

Sucralose

analytical standard

Synonyma:

1,6-Dichloro-1,6-dideoxy-β-D-fructofuranosyl-4-chloro-4-deoxy-α-D-galactopyranoside, E955, Trichlorosucrose

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About This Item

Empirický vzorec (Hillův zápis):
C12H19Cl3O8
Číslo CAS:
Molekulová hmotnost:
397.63
Beilstein/REAXYS Number:
3654410
EC Number:
MDL number:
UNSPSC Code:
85151701
PubChem Substance ID:
E Number:
E955
NACRES:
NA.24

grade

analytical standard

Quality Level

assay

≥98.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

SMILES string

OC[C@H]1O[C@H](O[C@]2(CCl)O[C@H](CCl)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@H]1Cl

InChI

1S/C12H19Cl3O8/c13-1-4-7(17)10(20)12(3-14,22-4)23-11-9(19)8(18)6(15)5(2-16)21-11/h4-11,16-20H,1-3H2/t4-,5-,6+,7-,8+,9-,10+,11-,12+/m1/s1

InChI key

BAQAVOSOZGMPRM-QBMZZYIRSA-N

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General description

Sucralose is a derivative of sucrose, which is generally used as a non-nutritive sweetener in foods and beverages.
Sucralose, belonging to the class of synthetic sweeteners, is a noncarcinogenic taste enhancer, found to be 400-800 times sweeter than sucrose. It is not involved in inducing glycemic response and is virtually noncaloric. Sucralose is used as a part of a comprehensive portfolio of analytical standards to monitor natural and artificial sugar substitutes in the food and beverage industries. This product finds applications as a sweetener in a variety of food products and beverages including desserts, bakery products, canned fruits/vegetables, dressings, breakfast cereals, confectionery, medical foods, dietary supplements, etc.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Sucralose may be used as an analytical reference standard for the quantification of the analyte in:
  • Commercial sugar-free products such as Splenda and Red Raspberry Diet Rite beverage using high performance anion-exchange (HPAE) chromatography coupled with pulsed amperometric detection (PAD).
  • Water and beverage samples using liquid chromatography/time-of-flight mass spectrometry (LC/TOF-MS).

Biochem/physiol Actions

A synthetic sweet tastant detectable by humans. Activates T1R2/T1R3 sweet taste receptors on enteroendocrine cells and elicits increased hormonal secretion of glucagon-like peptide-1 and glucose-dependent insulinotrophic peptide.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


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Osvědčení o analýze (COA)

Lot/Batch Number

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Determination of sucralose in splenda and a sugar-free beverage using high-performance anion-exchange chromatography with pulsed amperometric detection
Hanko PV, et al.
Journal of Agricultural and Food Chemistry, 52(14), 4375-4379 (2004)
An overview of the safety of sucralose
Grotz L.V and Munro C.I
Regulatory Toxicology and Pharmacology, 55(01), 1-5 (2009)
Food Analysis by HPLC, Second Edition (2000)
Mitchell.AE et al.
Formulation and Production Carbonated Soft Drinks (1990)
Analysis of sucralose and other sweeteners in water and beverage samples by liquid chromatography/time-of-flight mass spectrometry
Ferrer I and Thurman EM
Journal of Chromatography A, 1217(25), 4127-4134 (2010)

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