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Key Documents

MAB5618

Sigma-Aldrich

Anti-Serotonin Transporter Antibody

ascites fluid, Chemicon®

Synonyma:

SERT

Přihlásitk zobrazení cen stanovených pro organizaci a smluvních cen


About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

antibody form

ascites fluid

antibody product type

primary antibodies

clone

monoclonal

species reactivity

primate, human

should not react with

rat

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

Specificity

Serotonin Transporter, human and non-human primate.

Immunogen

Synthetic peptide from human serotonin transporter.

Application

Anti-Serotonin Transporter Antibody detects level of Serotonin Transporter & has been published & validated for use in IH.
Immunohistochemistry: 1:500-1:1,000 on 10% formalin fixed, paraffin embedded tissue from human Medulla oblongata. Suggested antigen retrieval method is Heat Induced Epitope Retrieval (HIER): Citrate Buffer pH 6.0.

Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Research Sub Category
Ion Channels & Transporters

Physical form

Ascites

Storage and Stability

Maintain at -20degC in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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Navštívit knihovnu dokumentů

Anke J Borgers et al.
Frontiers in neuroscience, 8, 106-106 (2014-05-27)
That serotonin plays a role in the regulation of feeding behavior and energy metabolism has been known for a long time. Serotonin transporters (SERT) play a crucial role in serotonin signaling by regulating its availability in the synaptic cleft. The
Jonas Woll Jørandli et al.
American journal of physiology. Gastrointestinal and liver physiology, 319(6), G761-G768 (2020-09-25)
Serotonin is a highly conserved and ubiquitous signaling molecule involved in a vast variety of biological processes. A majority of serotonin is produced in the gastrointestinal epithelium, where it is suggested to act as a prominent regulatory molecule in the
Smriti Patodia et al.
Brain pathology (Zurich, Switzerland), 32(5), e13074-e13074 (2022-04-29)
Several lines of evidence link deficient serotonin function and SUDEP. Chronic treatment with serotonin reuptake inhibitors (SRIs) reduces ictal central apnoea, a risk factor for SUDEP. Reduced medullary serotonergic neurones, modulators of respiration in response to hypercapnia, were reported in
C H Lew et al.
Molecular autism, 11(1), 12-12 (2020-02-07)
Williams syndrome (WS) and autism spectrum disorder (ASD) are neurodevelopmental disorders that demonstrate overlapping genetic associations, dichotomous sociobehavioral phenotypes, and dichotomous pathological differences in neuronal distribution in key social brain areas, including the prefrontal cortex and the amygdala. The serotonergic
Cheryl D Stimpson et al.
Social cognitive and affective neuroscience, 11(3), 413-422 (2015-10-18)
Humans' closest living relatives are bonobos (Pan paniscus) and chimpanzees (Pan troglodytes), yet these great ape species differ considerably from each other in terms of social behavior. Bonobos are more tolerant of conspecifics in competitive contexts and often use sexual

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