MAB5430

Anti-Tau Antibody, Caspase Cleaved (truncated at Asp421)

clone tau-C3, Chemicon^®, from mouse

• UNSPSC Code: 12352203
• NACRES: NA.41
• eCl@ss: 32160702
• Clone: tau-C3, monoclonal
• Species reactivity: human
• Application: ELISA, IHC, WB
• Citations: 14

Properties

• biological source: mouse
• Quality Segment: 100
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: tau-C3, monoclonal
• species reactivity: human
• manufacturer/tradename: Chemicon^®
• technique(s): ELISA: suitable, immunohistochemistry: suitable, western blot: suitable
• isotype: IgG1
• NCBI accession no.: NM_005910.3, NM_016834.2, NM_016835.2, NM_016841.2
• UniProt accession no.: P10636
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... MAPT(4137)

Description

General description

43 kDa (aa 1 to 421) or smaller fragments with Asp421 as the c-terminus

Immunogen

Epitope: Caspase Cleaved (truncated at Asp421)

Peptide corresponding to the C-terminus of tau truncated as aspartic acid 421.

Application

Anti-Tau Antibody, Caspase Cleaved (truncated at Asp421) is an antibody against Tau for use in ELISA, WB, IH.

Research Category
Neuroscience

Research Sub Category
Neurodegenerative Diseases

Western blot

Immunohistochemistry

ELISA

Optimal working dilutions must be determined by end user.

Biochem/physiol Actions

Reacts with Tau, caspase cleaved (truncated at Asp421). The antibody shows no reactivity with full length tau nor other tau C-terminal truncations. The antibody stains amyloid beta treated neurons and brain tissue in Alzheimer′s disease, more specifically it stains a subset of neurofibrillary tangles, tau-containing neuritic plaques and neuropil threads.

Physical form

Format: Purified

Purified immunoglobulin. Liquid in PBS. Contains no preservative.

Preparation Note

Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• Storage Class: 12 - Non Combustible Liquids