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Caffeine

Name: Caffeine
Brand: MM
Price: 164 USD
Availability: InStock

≥99% (HPLC), central nervous system stimulant, solid

Synonym(s):

Caffeine, 3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione

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Size/SKU	Availability	Price
500 g	Estimated to ship onJune 17, 2026	$164.00

About This Item

Empirical Formula (Hill Notation):

C₈H₁₀N₄O₂

CAS Number:

58-08-2

Molecular Weight:

194.19

UNSPSC Code:

12352200

NACRES:

NA.77

MDL number:

MFCD00005758

Assay:

≥99% (HPLC)

Form:

solid

Storage condition:

OK to freeze

$164.00

Estimated to ship onJune 17, 2026Details

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Properties

Product Name

Caffeine, Trimethylated xanthine that acts as a potent central nervous system stimulant.

description

Merck USA index - 14, 1636

Quality Segment

100

assay

≥99% (HPLC)

form

solid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze

color

white

solubility

chloroform: 50 mg/mL

shipped in

ambient

storage temp.

10-30°C

SMILES string

[n]1(c2c(nc1)N(C(=O)N(C2=O)C)C)C

InChI

1S/C8H10N4O2/c1-10-4-9-6-5(10)7(13)12(3)8(14)11(6)2/h4H,1-3H3

InChI key

RYYVLZVUVIJVGH-UHFFFAOYSA-N

Description

General description

Trimethylated xanthine that acts as a potent central nervous system stimulant. At higher doses, produces tachycardia and interferes with the uptake and storage of Ca²⁺by the sarcoplasmic reticulum in skeletal muscle. Prevents apoptosis and cell cycle effects induced by Camptothecin (Cat. No. 208925 ) and topotecan in HL-60 cells.

Biochem/physiol Actions

Cell permeable: no

Primary Target
Potent central nervous system stimulant

Product does not compete with ATP.

Reversible: no

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Zhen, W., and Vaugha, A. T. 1995. Radiat. Res.141, 170.
Howell, L. L. 1993. Cancer Res.54, 4993.
Traganos, F., et al. 1993. Cancer Res.53, 4613.
Zahradnik, I., and Palade, P. 1993. Pflugers Arch. 424, 129.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Harmful (C)

Compare Similar Items

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Show Differences

1 of 1

This Item	C7731	1.02584	56396
Sigma-Aldrich 205548 Caffeine	Sigma-Aldrich C7731 Caffeine	SAFC 1.02584 Caffeine	Supelco 56396 Caffeine
form solid	form crystalline, powder	form crystalline powder	form -
assay ≥99% (HPLC)	assay -	assay 98.5-101.0% (HPLC), 98.5-101.0% (perchloric acid titration)	assay -
manufacturer/tradename Calbiochem^®	manufacturer/tradename -	manufacturer/tradename -	manufacturer/tradename Manufactured by: Sigma-Aldrich Production GmbH, Switzerland
Quality Level 100	Quality Level 200	Quality Level 500	Quality Level 300
storage temp. 10-30°C	storage temp. -	storage temp. 2-30°C	storage temp. -
storage condition OK to freeze	storage condition -	storage condition -	storage condition -

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pictograms

GHS07

signalword

Warning

hcodes

H302

pcodes

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 1

Certificates of Analysis (COA)

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