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Eshmuno^® CMX Resin

Eshmuno® CMX

• Synonyma: Eshmuno^® CMX
• UNSPSC Code: 47101511

Vlastnosti

• ligand: (Carboxy and Alkyl Group)
• Quality Level: 400
• sterility: sterile (Caustic Stable)
• form: resin
• specific analyte(s): MAbs
• parameter: 300 cm/hr flow rate; 8 bar max. pressure
• matrix active group: polymer, polyvinyl ether
• mean particle size: 50 μm
• capacity: 60 mg binding capacity (pIgG/ml of resin)
• application(s): ADC; mAb
• separation technique: mixed mode
• storage temp.: 2-30°C

Popis

General description

Eshmuno^® CMX chromatography resin is a mixed mode chromatography resin built on the proven Eshmuno^® resin technology. This innovative resin combines weak cation exchange properties with hydrophobic interaction, providing high selectivity for Monoclonal Antibody (mAb), fusion protein and Antibody Drug Conjugate (ADCs) purification as well as separation of low molecular weight impurities, Host Cell Proteins (HCPs) and glycovariants.

Application

Purification of mAbs, ADCs, fusion proteins

Features and Benefits

Eshmuno^® CMX chromatography resin enables users to

• Intensify processes and decrease costs by reducing the number of chromatographic steps and buffer consumption
• Improve performance with higher recovery rates, high selectivity and superior dynamic binding capacity
• Improve the user experience with a broad operational window, simplified process development and easy column packing due to a rigid base bead

Legal Information

Eshmuno is a registered trademark of Merck KGaA, Darmstadt, Germany

Bezpečnostní informace

• pictograms: GHS02
• signalword: Warning
• hcodes: H226
• pcodes: P210 - P233 - P240 - P241 - P242 - P243
• Hazard Classifications: Flam. Liq. 3
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 3
• flash_point_f: 95.0 °F
• flash_point_c: 35 °C