Skip to Content
Merck
  • FeCl3 catalyzed Prins-type cyclization for the synthesis of highly substituted indenes: application to the total synthesis of (±)-jungianol and epi-jungianol.

FeCl3 catalyzed Prins-type cyclization for the synthesis of highly substituted indenes: application to the total synthesis of (±)-jungianol and epi-jungianol.

Organic letters (2013-01-16)
Dattatraya H Dethe, Ganesh Murhade
PMID23317410
ABSTRACT

A novel approach was developed for the synthesis of highly substituted indene derivatives, using an FeCl(3) catalyzed Prins-type cyclization reaction which was further applied in the total synthesis of jungianol and epi-jungianol.

MATERIALS
Product Number
Brand
Product Description
451649
Sigma-Aldrich
Iron(III) chloride, anhydrous, powder, ≥99.99% trace metals basis
701122
Sigma-Aldrich
Iron(III) chloride, sublimed grade, ≥99.9% trace metals basis
F2877
Sigma-Aldrich
Iron(III) chloride hexahydrate, reagent grade, ≥98%, chunks
236489
Sigma-Aldrich
Iron(III) chloride hexahydrate, ACS reagent, 97%
44944
Sigma-Aldrich
Iron(III) chloride hexahydrate, puriss. p.a., ACS reagent, crystallized, 98.0-102% (RT)
710857
Sigma-Aldrich
Iron(III) chloride solution, 0.2 M in 2-methyltetrahydrofuran
80353
Millipore
TDA Reagent, suitable for microbiology
12322
Sigma-Aldrich
Iron(III) chloride solution, purum, 45% FeCl3 basis