[Indoor air guide values for ethylbenzene].

[Indoor air guide values for ethylbenzene].

Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz (2012-09-01)

ABSTRACT

The German Working Group on Indoor Guidelines of the Federal Environment Agency and the States' Health Authorities is issuing indoor air guide values to protect public health. No human studies are available for health evaluation of ethylbenzene in indoor air. In a well documented subchronic inhalation animal study assessed as reliable, ototoxic effects were observed (LOAECsubchronic = 870 mg/m³). The Working Group assessed a LAEC of 186 mg ethylbenzene/m³ for the endpoint ototoxicity. By applying a factor of 2 to extrapolate from subchronic to chronic exposure, an interspecies factor of 2.5, a factor of 10 for interindividual variability, and a factor of 2 to account for the higher respiratory rate of children compared to adults, a health hazard guide value (RW II) of 2 mg ethylbenzene/m³ is obtained. A precautionary guide value (RW I) of 0.2 mg ethylbenzene/m³ is recommended.

MATERIALS

Product Number

Brand

Product Description

736198

Supelco

Ethylbenzene solution, NMR reference standard, 10% in chloroform-d (99.8 atom % D), NMR tube size 5 mm × 8 in. , ultra-thin wall

708046

Sigma-Aldrich

Ethylbenzene solution, NMR reference standard, 10% in chloroform-d (99.8 atom % D)

612065

Sigma-Aldrich

Ethylbenzene solution, NMR reference standard, 0.1% in chloroform-d (99.8 atom % D), TMS 0.01 %, NMR tube size 10 mm × 8 in.

612480

Supelco

Ethylbenzene solution, NMR reference standard, 0.1% in chloroform-d (99.8 atom % D), chromium(III) acetylacetonate 0.1 mg/mL, TMS 0.01 %, NMR tube size 5 mm × 8 in.

487104

Supelco

Ethylbenzene solution, NMR reference standard, 0.1% in chloroform-d (99.8 atom % D), TMS 0.01 %, NMR tube size 5 mm × 8 in.

487120

Sigma-Aldrich

Ethylbenzene solution, NMR reference standard, 0.1% in chloroform-d (99.8 atom % D), TMS 0.01 %, NMR tube size 8 mm × 8 in.

551341

Sigma-Aldrich

Ethylbenzene solution, NMR reference standard, 5% in chloroform-d (99.8 atom % D), TMS 2 %, NMR tube size 5 mm × 8 in.

714917

Sigma-Aldrich

Ethylbenzene solution, NMR reference standard, 0.1% in chloroform-d (99.8 atom % D), TMS 0.01 %, NMR tube size 5 mm × 8 in. , ultra-thin wall

296848

Sigma-Aldrich

Ethylbenzene, anhydrous, 99.8%

03079

Supelco

Ethylbenzene, analytical standard

E12508

Sigma-Aldrich

Ethylbenzene, ReagentPlus^®, 99%