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Merck

Synthesis of novel series of malonamides derivatives via a five-component reaction.

Molecular diversity (2013-05-25)
Abbas Rahmati, Tahmineh Kenarkoohi, Mahdi Ahmadi-Varzaneh
RESUMEN

A one-pot, five-component condensation reaction of isocyanide, Meldrum's acid, arylidene malononitrile, and two amine molecules in CH2Cl2 at ambient temperature to give malonamide derivatives is described.

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Sigma-Aldrich
Malonamide, 97%