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Merck

Ultrasonic resonant modes of piezoelectric balloons under internal pressure.

The Journal of the Acoustical Society of America (2012-09-18)
Lori Vidal Denham, David A Rice
RESUMEN

Properties of a piezoelectric polymeric angioplasty balloon that may decrease the problems of acute closure and restenosis are evaluated in this study. Polyvinylidene difluoride (PVDF), a piezoelectric and pyroelectric polymer, has sufficient strength to serve as a standard angioplasty balloon as well as functioning as an ultrasonic transmitter and/or receiver. These properties enable potential therapeutic applications using ultrasound such as plaque ablation and sonotherapy as well as vulnerable plaque diagnosis using thermography. This study investigates the resonant structure of the PVDF balloon catheter in the frequency range 5-100 kHz. Vibrations of the piezoelectric balloon are modeled using cylindrical shell theory and compared with the observed modal frequencies of PVDF cylinders with and without internal pressure. Modal frequencies are determined by measuring the near-field pressure response of the PVDF cylinders using a high frequency microphone. A rich nodal structure is observed between 5 and 100 kHz with peak relative amplitudes measured between 42 and 45 kHz. Higher order modes for cylinders with 9 μm and 28 μm wall thickness increase in frequency as the internal pressure is increased. Experimental measurements confirm theoretical models that predict both pressure-dependent and pressure-independent resonant frequencies. Frequencies of pressure-dependent modes are calculated within 2.2% of measured values at high pressure.

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Sigma-Aldrich
Poly(vinylidene fluoride), average Mw ~534,000 by GPC, powder
Sigma-Aldrich
Poly(vinylidene fluoride), average Mw ~530,000, pellets
Sigma-Aldrich
Poly(vinylidene fluoride), average Mw ~180,000 by GPC, average Mn ~71,000, beads or pellets
Sigma-Aldrich
Poly(vinylidene fluoride), average Mw ~275,000 by GPC, average Mn ~107,000, pellets