Nicotinamide adenine dinucleotide: beyond a redox coenzyme.

Nicotinamide adenine dinucleotide: beyond a redox coenzyme.

Organic & biomolecular chemistry (2007-11-21)

Hening Lin

PMID18019526

RESUMEN

ADP-ribosylation using nicotinamide adenine dinucleotide (NAD+) is an important type of enzymatic reaction that affects many biological processes. A brief introductory review is given here to various ADP-ribosyltransferases, including poly(ADP-ribose) polymerase (PARPs), mono(ADP-ribosyl)-transferases (ARTs), NAD(+)-dependent deacetylases (sirtuins), tRNA 2'-phosphotransferases, and ADP-ribosyl cyclases (CD38 and CD157). Focus is given to the enzymatic reactions, mechanisms, structures, and biological functions.

MATERIALES

Referencia del producto

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Descripción del producto

N8129

Sigma-Aldrich

β-Nicotinamide adenine dinucleotide, reduced disodium salt hydrate, ≥97% (HPLC)

N4505

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β-Nicotinamide adenine dinucleotide, reduced dipotassium salt

N8285

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β-Nicotinamide adenine dinucleotide, pkg of 10 mg (per vial)

N8535

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β-Nicotinamide adenine dinucleotide, pkg of 50 mg (per vial)

N6785

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β-Nicotinamide adenine dinucleotide, reduced disodium salt, ~98%, pkg of 10 mg (per vial)

N8410

Sigma-Aldrich

β-Nicotinamide adenine dinucleotide, pkg of 20 mg (per vial)

N7410

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β-Nicotinamide adenine dinucleotide, reduced disodium salt, ~98%, pkg of 2 mg (per vial)

N1161

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β-Nicotinamide adenine dinucleotide, reduced disodium salt hydrate, ~98%, pkg of 100 mg

N0786

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β-Nicotinamide adenine dinucleotide, reduced disodium salt, ~98%, pkg of 1 mg (per vial)

N6005

Sigma-Aldrich

β-Nicotinamide adenine dinucleotide, reduced disodium salt hydrate, ≥94% (HPLC)

N9410

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β-Nicotinamide adenine dinucleotide, reduced disodium salt, ~98%, pkg of 5 mg (per vial)

N7132

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β-Nicotinamide adenine dinucleotide lithium salt from Saccharomyces cerevisiae, ≥95%

N6660

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β-Nicotinamide adenine dinucleotide, reduced disodium salt, ~98%, pkg of 0.2 mg (per vial)

N9535

Sigma-Aldrich

β-Nicotinamide adenine dinucleotide, reduced disodium salt, ~98%, pkg of 25-30 mg (per vial)