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C0250

Sigma-Aldrich

Sodium cacodylate trihydrate

≥98%

Synonym(s):

Cacodylic acid sodium salt trihydrate, Dimethylarsinic acid sodium salt, Dimethylarsonic acid sodium salt

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About This Item

Linear Formula:
(CH3)2AsO2Na · 3H2O
CAS Number:
6131-99-3
Molecular Weight:
214.03
Beilstein:
3702348
EC Number:
204-708-2
MDL number:
MFCD00149079
UNSPSC Code:
12161700
PubChem Substance ID:
24892242
NACRES:
NA.21

Assay

≥98%

form

powder

pH

5.1-7.4

pKa (25 °C)

6.27

solubility

water: 100 mg/mL, clear, colorless

application(s)

ADME/TOX

storage temp.

room temp

SMILES string

[Na+].[H]O[H].[H]O[H].[H]O[H].C[As](C)([O-])=O

InChI

1S/C2H7AsO2.Na.3H2O/c1-3(2,4)5;;;;/h1-2H3,(H,4,5);;3*1H2/q;+1;;;/p-1

InChI key

RLGWPHBPRCROJO-UHFFFAOYSA-M

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General description

Sodium cacodylate is an organic arsenic compound that is metabolized to produce inorganic, trivalent arsenic in vivo. Sodium cacodylate has been used as a source of arsenic in toxicological research. It is used as a buffer with an effective pH buffering range of 5.1-7.4. In microscopy studies, the buffering capacity of cacodylate prevents excess acidity that may result from tissue fixation.

Application

Sodium cacodylate trihydrate has been used in the stabilization of the fixatives for electron microscopy. It has also been used to collect vibratome sections to perform nucleoside-diphosphatase technique.

Signal Word

Danger

Hazard Statements

H301 + H331,H350,H410

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B

Storage Class Code

6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Subcellular adaptation of the human diaphragm in chronic obstructive pulmonary disease
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