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182750

Millipore

ASB-14

A zwitterionic amidosulfobetaine detergent useful for solubilizing proteins visualized by 2D-electrophoresis.

Synonym(s):

ASB-14

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About This Item

Empirical Formula (Hill Notation):
C22H46N2O4S
Molecular Weight:
434.68
UNSPSC Code:
12161902
NACRES:
NA.21

Quality Level

100

Assay

≥97% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
desiccated (hygroscopic)

color

white to off-white

solubility

water: 50 mg/mL

shipped in

ambient

storage temp.

10-30°C

General description

A zwitterionic amidosulfobetaine detergent that exhibits better protein extraction properties than CHAPS.
A zwitterionic amidosulfobetaine detergent useful for solubilizing proteins visualized by 2D-electrophoresis. The increased solubilization produced by this detergent enables the identification of previously undetected membrane proteins.

Application


  • Effect of bovine pericardial extracellular matrix scaffold niche on seeded human mesenchymal stem cell function.: This paper explores the influence of the bovine pericardial extracellular matrix on human mesenchymal stem cells, with ASB-14 used to modulate cellular responses. The research contributes to advancements in scaffold-based tissue engineering (Liu et al., 2016).

  • In vivo xenogeneic scaffold fate is determined by residual antigenicity and extracellular matrix preservation.: Investigating the fate of xenogeneic scaffolds in vivo, this study shows that ASB-14 helps maintain extracellular matrix integrity and reduce antigenicity, which is critical for successful scaffold integration and function in tissue engineering (Wong et al., 2016).

Warning

Toxicity: Irritant (B)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 year at -20°C.

Other Notes

Carroll, J., et al. J. Biol. Chem.277, 50311.
Herbert, B. 1999. Electrophoresis20, 660.
Chevallet, M. et al. 1998. Electrophoresis 19, 1901.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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