H3878

Hyodeoxycholic acid

≥98%

• Sinónimos: 3α,6α-Dihydroxy-5β-cholan-24-oic acid
• Fórmula empírica (notación de Hill): C₂₄H₄₀O₄
• Número de CAS: 83-49-8
• Peso molecular: 392.57
• EC Number: 201-483-2
• MDL number: MFCD00003681
• UNSPSC Code: 12352106
• PubChem Substance ID: 24895601
• NACRES: NA.77

Propiedades

• assay: ≥98%
• mp: 200-201 °C (lit.)
• SMILES string: C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3C[C@H](O)[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
• InChI: 1S/C24H40O4/c1-14(4-7-22(27)28)17-5-6-18-16-13-21(26)20-12-15(25)8-10-24(20,3)19(16)9-11-23(17,18)2/h14-21,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15-,16+,17-,18+,19+,20+,21+,23-,24-/m1/s1
• InChI key: DGABKXLVXPYZII-SIBKNCMHSA-N
• Gene Information: human ... NR1H2(7376) , NR1H3(10062)

Descripción

General description

Hyodeoxycholic acid is a naturally occurring secondary bile acid. It is produced by the gut flora in the small intestine. Hyodeoxycholic acid is obtained from chenodeoxycholic acid during enterohepatic circulation of bile in rats.

Application

Hyodeoxycholic acid has been used:

• as a standard for serum bile acid profiling by liquid chromatography-mass spectrometry (LC-MS) method in rat cells.
• as a component of the growth medium to study its effect as an anti-aging small molecule on the chronological life span (CLS) of the pex5Δ (Δ) strain.
• as a standard for analyzing bile acid composition and total bile acids in mice cells.

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)