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Merck

G5792

SAFC

L-Glutamina

Fabricación farmacéutica

Sinónimos:

Ácido L-glutámico 5-amida, Levoglutamida, Ácido (S)-2,5-diamino-5-oxopentanoico

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About This Item

Fórmula lineal:
H2NCOCH2CH2CH(NH2)CO2H
Número de CAS:
Peso molecular:
146.14
Beilstein/REAXYS Number:
1723797
EC Number:
MDL number:
UNSPSC Code:
12352209
eCl@ss:
32160406
NACRES:
NA.26

biological source

non-animal source

Quality Level

assay

≥99%

form

powder

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, heavy metals, residual solvents, tested

mp

185 °C (dec.) (lit.)

solubility

H2O: 25 mg/mL

application(s)

pharmaceutical (small molecule)

foreign activity

cytotoxicity, tested

SMILES string

N[C@@H](CCC(N)=O)C(O)=O

InChI

1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m0/s1

InChI key

ZDXPYRJPNDTMRX-VKHMYHEASA-N

Gene Information

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General description

Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.
To request documentation for this product, please contact Customer Support and select ‘Product Documentation′. Please note that access to the documentation for this product requires a confidentiality disclosure agreement.

Application

L-Glutamine is an essential amino acid that is a crucial component of culture media that serves as a major energy source for cells in culture. L-Glutamine is very stable as a dry powder and as a frozen solution. In liquid media or stock solutions, however, L-Glutamine degrades relatively rapidly. Optimal cell performance usually requires supplementation of the media with L-Glutamine prior to use.

Biochem/physiol Actions

La L-glutamina es un aminoácido esencial que es un componente crucial de los medios de cultivo donde actúa como una fuente importante de energía para las células en cultivo. La L-glutamina es muy estable en forma de polvo seco y de disolución congelada. En los medios líquidos o las disoluciones de reserva, sin embargo, la L-glutamina se degrada con relativa rapidez. El rendimiento celular óptimo normalmente requiere la suplementación de los medios con L-glutamina antes de su uso.

Legal Information

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificados de análisis (COA)

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Importance and uses of glutamine in hybridoma and mammalian cell culture

Importance and uses of glutamine in hybridoma and mammalian cell culture

Importance and uses of glutamine in hybridoma and mammalian cell culture

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Chromatograms

application for HPLC

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