Saltar al contenido
Merck

M4125

Sigma-Aldrich

D-Manitol

≥98% (GC)

Sinónimos:

manitol

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización


About This Item

Fórmula empírica (notación de Hill):
C6H14O6
Número de CAS:
Peso molecular:
182.17
Beilstein/REAXYS Number:
1721898
EC Number:
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:
NACRES:
NA.21

biological source

plant

Quality Level

assay

≥98% (GC)

form

powder

color

white

useful pH range

5.0-6.5 (25 °C, 182 g/L, (77 °F ))

solubility

water: 100 mg/mL, clear, colorless

storage temp.

room temp

SMILES string

OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

InChI

1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1

InChI key

FBPFZTCFMRRESA-KVTDHHQDSA-N

¿Está buscando productos similares? Visita Guía de comparación de productos

General description

D-Mannitol, a naturally occurring six-carbon sugar alcohol or polyol, is found in plants such as algae, onions, grasses, and olives. It is considered safe due to its relatively lower glycemic index than sucrose.

Application

D-Mannitol has been used:
  • in osmotic loading to adjust the osmolarity of solutions
  • as a component of test sugar solution for cellobiose-mannitol permeability test
  • as an internal standard in nuclear magnetic resonance (NMR) to compare/analyze the mannitol concentrations in urine samples
  • to treat the control cells and regulate the osmotic pressure of high glucose

D-mannitol has been used as a hydroxyl radical scavenger and as a medium supplement.

Biochem/physiol Actions

D-Mannitol may play an important role in lipolysis and fat oxidation as it can enhance the phosphorylation of AMP-activated protein kinase (AMPK) and acetyl-CoA carboxylase 1 (ACC). It serves as an anti-obesity supplement. D-Mannitol stimulates the synthesis of short-chain fatty acids (SCFAs), which regulate lipid metabolism in the liver.
Un alditol edulcorante. Utilizado en estudios de inhibición del dulzor.

Other Notes

To gain a comprehensive understanding of our extensive range of Sugar alcohols for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

ppe

Eyeshields, Gloves, type N95 (US)


Elija entre una de las versiones más recientes:

Certificados de análisis (COA)

Lot/Batch Number

¿No ve la versión correcta?

Si necesita una versión concreta, puede buscar un certificado específico por el número de lote.

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Los clientes también vieron

S J Upton et al.
Journal of clinical microbiology, 33(2), 371-375 (1995-02-01)
Surface-sterilized oocysts of Cryptosporidium parvum were applied to subconfluent monolayers of human adenocarcinoma (HCT-8) cells grown on coverslips in six-well cluster plates. Parasite-infected cultures were then incubated in RPMI 1640 with 10% fetal bovine serum, 15 mM HEPES (N-2-hydroxyethylpiperazine-N'-2-ethanesulfonic acid)
A Matsuzaki et al.
Cancer research, 49(20), 5702-5707 (1989-10-15)
Rat 3Y1 fibroblasts transformed by the E1A gene of adenovirus type 12 (E1A-3Y1 cells) are highly sensitive to the cell-killing effect of 1,3-dilinoleoylglycerol (DLG) administered in a culture medium, whereas the parental 3Y1 cells are less sensitive (H. Shimura et
Heikki O Koskela et al.
Chest, 125(6), 1985-1992 (2004-06-11)
To define whether coughing during mannitol challenge is a nonspecific side effect of this challenge or is associated with asthma. A prospective study. University hospital. Thirty-seven steroid-naive, asthmatic subjects and 10 healthy subjects. The participants completed a symptom questionnaire, recorded
Diana Bilton et al.
Thorax, 69(12), 1073-1079 (2014-09-24)
Bronchiectasis is characterised by excessive production of mucus and pulmonary exacerbations. Inhaled osmotic agents may enhance mucociliary clearance, but few long-term clinical trials have been conducted. To determine the impact of inhaled mannitol on exacerbation rates in patients with non-cystic
Marieke Dubois et al.
Plant physiology, 169(1), 166-179 (2015-05-23)
Leaf growth is a tightly regulated and complex process, which responds in a dynamic manner to changing environmental conditions, but the mechanisms that reduce growth under adverse conditions are rather poorly understood. We previously identified a growth inhibitory pathway regulating

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico