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Merck

840029P

Avanti

18:0 PS

Avanti Research - A Croda Brand

Sinónimos:

1,2-dioctadecanoyl-sn-glycero-3-phospho-L-serine (sodium salt); DSPS; PS(18:0/18:0); 110671

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About This Item

Fórmula empírica (notación de Hill):
C42H81NO10PNa
Número de CAS:
Peso molecular:
814.06
UNSPSC Code:
12352211
NACRES:
NA.25

description

1,2-distearoyl-sn-glycero-3-phospho-L-serine (sodium salt)

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (840029P-10mg)
pkg of 1 × 25 mg (840029P-25mg)
pkg of 1 × 500 mg (840029P-500mg)

manufacturer/tradename

Avanti Research - A Croda Brand

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[Na+]

InChI

1S/C42H82NO10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(44)50-35-38(36-51-54(48,49)52-37-39(43)42(46)47)53-41(45)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h38-39H,3-37,43H2,1-2H3,(H,46,47)(H,48,49);/q;+1/p-1/t38-,39+;/m1./s1

InChI key

SJRBMGBLPUBGJL-MBAWARMDSA-M

General description

Phosphatidylserine (PS), an aminophospholipid is negatively charged and accounts for 2–10% of total cellular lipid. It is located in the membrane leaflets.

Application

18:0 PS has been used to evaluate its affinity to cytochrome c using surface plasmon resonance (SPR) technique and in the preparation of phospholipid vesicles. It may be used in the preparation of polydimethylsiloxane (PDMS) hybrid microbubbles.

Biochem/physiol Actions

Phosphatidylserine (PS) plays a key role in protein kinase C pathways. It also helps in confining the intracellular proteins to membrane leaflets of cytosol.

Packaging

20 mL Clear Glass Screw Cap Vial (840029P-500mg)
5 mL Amber Glass Screw Cap Vial (840029P-10mg)
5 mL Amber Glass Screw Cap Vial (840029P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

also commonly purchased with this product

Referencia del producto
Descripción
Precios

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Kanaka Hettiarachchi et al.
Journal of colloid and interface science, 344(2), 521-527 (2010-02-19)
Polymer-lipid microbubbles (PLBs) are generated by microfluidic flow-focusing devices to form a new class of long-lasting hybrid particles. The specific PLB construct developed is an elastic gas-filled microsphere with a polydimethylsiloxane (PDMS) shell containing phospholipids conjugated to functionalized polyethyleneglycol (PEG).
Carolina Varela Chavez et al.
Cellular microbiology, 17(10), 1477-1493 (2015-04-18)
Clostridium sordellii lethal toxin (TcsL) is a potent virulence factor belonging to the large clostridial glucosylating toxin family. TcsL enters target cells via receptor-mediated endocytosis and delivers the N-terminal catalytic domain (TcsL-cat) into the cytosol upon an autoproteolytic process. TcsL-cat
Pooja Jha et al.
Cell systems, 6(6), 709-721 (2018-06-18)
The genetic regulation and physiological impact of most lipid species are unexplored. Here, we profiled 129 plasma lipid species across 49 strains of the BXD mouse genetic reference population fed either chow or a high-fat diet. By integrating these data with genomics
German Stepanov et al.
FEBS letters, 583(1), 97-100 (2008-12-09)
We attempted to evaluate the affinity of the anionic phospholipids to cytochrome c by means of surface plasmon resonance (SPR) technique and to correlate it with the cytochrome c active site alterations and peroxidase activity. Our experiments showed a strong
Jung Yong Eum et al.
Journal of chromatography. A, 460849-460849 (2020-01-14)
Aging refers to the intracellular accumulation of reactive oxygen species that damages proteins, DNA, and lipids. As alterations in lipid metabolism may trigger metabolic disorders and the onset of metabolic diseases, changes in lipid profiles can be closely related to

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