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Merck

74104

Sigma-Aldrich

4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride

≥97.0% (calc. on dry substance, AT), for peptide synthesis

Sinónimos:

DMTMM, MMTM

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About This Item

Fórmula empírica (notación de Hill):
C10H17ClN4O3
Número de CAS:
Peso molecular:
276.72
Beilstein/REAXYS Number:
8026872
MDL number:
UNSPSC Code:
12352005
PubChem Substance ID:
NACRES:
NA.22

product name

4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride, 95% (HPLC)

assay

95% (HPLC)

form

powder

reaction suitability

reaction type: Coupling Reactions

impurities

≤17 wt. % water

application(s)

peptide synthesis

storage temp.

−20°C

SMILES string

[Cl-].COc1nc(OC)nc(n1)[N+]2(C)CCOCC2

InChI

1S/C10H17N4O3.ClH/c1-14(4-6-17-7-5-14)8-11-9(15-2)13-10(12-8)16-3;/h4-7H2,1-3H3;1H/q+1;/p-1

Inchi Key

BMTZEAOGFDXDAD-UHFFFAOYSA-M

Application

4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride can be used as a condensing agent for the following transformations:
  • Condensation of carboxylic acids and amines to the corresponding amides in tetrahydrofuran.
  • Esterification of carboxylic acids with alcohols to the corresponding esters.
  • Conversion of carboxylic acids to the corresponding Weinreb amides in protic solvents.

Reagent for activating carboxylic acids in solution and solid phase peptide synthesis; superior or comparable to the most popular coupling reagents

pictograms

CorrosionExclamation mark

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 4 Oral - Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

wgk_germany

WGK 3

flash_point_f

198.5 °F - closed cup

flash_point_c

92.5 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Chameen Samarawickrama et al.
Cornea, 37(5), 609-616 (2017-11-28)
To describe the use of collagen-based alternatives to cyanoacrylate glue for the sealing of acute corneal perforations. A collagen analog comprising a collagen-like peptide conjugated to polyethylene glycol (CLP-PEG) and its chemical crosslinker were tested for biocompatibility. These CLP-PEG hydrogels
Tetrahedron, 55, 13159-13159 (1999)
Esterification of carboxylic acids with alcohols by 4-(4, 6-dimethoxy-1, 3, 5-triazin-2-yl)-4-methyl-morpholinium chloride (DMTMM).
Kunishima M
Synlett, 1999(08), 1255-1256 (1999)
Synthesis and characterization of 4-(4, 6-dimethoxy-1, 3, 5-triazin-2-yl)-4-methylmorpholinium chloride.
Kunishima M
Tetrahedron Letters, 40(29), 5327-5330 (1999)
Vianney Delplace et al.
Biomacromolecules, 21(6), 2421-2431 (2020-04-11)
A hydrogel that can deliver both proteins and cells enables the local microenvironment of transplanted cells to be manipulated with a single injection. Toward this goal, we designed a hydrogel suitable for the co-delivery of neural stem cells and chondroitinase

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