426R-1

STAT6 (EP325) Rabbit Monoclonal Primary Antibody

• Synonym(s): Signal Transducer and Activator of Transcription
• UNSPSC Code: 12352203

Properties

• biological source: rabbit
• Quality Level: 100; 500
• conjugate: unconjugated
• antibody form: culture supernatant
• antibody product type: primary antibodies
• clone: EP325, monoclonal
• description: For In Vitro Diagnostic Use in Select Regions
• form: buffered aqueous solution
• species reactivity: human
• packaging: vial of 0.1 mL concentrate (426R-14); vial of 0.1 mL concentrate Research Use Only (426R-14-RUO); vial of 0.5 mL concentrate (426R-15); vial of 1.0 mL concentrate (426R-16); vial of 1.0 mL concentrate Research Use Only (426R-16-RUO); vial of 1.0 mL pre-dilute Research Use Only (426R-17-RUO); vial of 1.0 mL pre-dilute ready-to-use (426R-17); vial of 7.0 mL pre-dilute ready-to-use (426R-18); vial of 7.0 mL pre-dilute ready-to-use Research Use Only (426R-18-RUO)
• manufacturer/tradename: Cell Marque^™
• technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated)
• isotype: IgG
• control: solitary fibrous tumor
• shipped in: wet ice
• storage temp.: 2-8°C
• visualization: nuclear
• Gene Information: human ... STAT6(6778)

Description

General description

STAT6, a member of the signal transducers and activators of transcription (STAT) family, has been found to form recurrent fusions with NAB2 on chromosome 12q13 in the majority of solitary fibrous tumors. Inactivated STAT6 can be found in the form of a dimer located in the cytoplasm. STAT6 and NAB2 fusion enables cytosolic STAT6 to migrate to the nucleus and thus allowing for detection in immunohistochemical assays. NAB2-STAT6 fusion transcriptions have been reported in the majority of solitary fibrous tumors but not in meningiomas, hemangioblastomas, schwannomas, and hemangiomas. This makes STAT6 a useful marker in distinguishing solitary fibrous tumors from other morphologically similar tumors.

Quality

IVD

IVD

IVD

RUO

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Preparation Note

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Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable