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Synthesis of 3-fluoroazetidines.

The Journal of organic chemistry (2006-08-26)
Willem Van Brabandt, Guido Verniest, Dirk De Smaele, Guillaume Duvey, Norbert De Kimpe
RÉSUMÉ

N-(Alkylidene or 1-arylmethylidene)-2-propenylamines were regiospecifically functionalized to novel N-(alkylidene or 1-arylmethylidene)-3-bromo-2-fluoropropylamines, which were proven to be excellent precursors for 3-fluoroazetidines.

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Sigma-Aldrich
Triethylamine trihydrofluoride, 97%