SML0252

Anisodamine

≥98% (HPLC)

• Synonyme(s) : α-(Hydroxymethyl)-benzeneacetic acid 6-hydroxy-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, 6β-Hydroxyhyoscyamine, 6-Hydroxyhyoscyamine
• Formule empirique (notation de Hill): C₁₇H₂₃NO₄
• Numéro CAS: 55869-99-3
• Poids moléculaire : 305.37
• Code UNSPSC : 12352116
• Nomenclature NACRES : NA.77

Propriétés

• Niveau de qualité: 100
• Pureté: ≥98% (HPLC)
• Forme: powder
• Couleur: white to beige
• Solubilité: H₂O: ≥5 mg/mL
• Température de stockage: room temp
• Chaîne SMILES: CN1[C@H]2C(O)C[C@@H]1C[C@H](OC(C(CO)C3=CC=CC=C3)=O)C2
• InChI: 1S/C17H23NO4/c1-18-12-7-13(9-15(18)16(20)8-12)22-17(21)14(10-19)11-5-3-2-4-6-11/h2-6,12-16,19-20H,7-10H2,1H3/t12-,13-,14+,15+,16-/m0/s1
• Clé InChI: WTQYWNWRJNXDEG-RBZJEDDUSA-N

Description

Description générale

Racemic mixture of diastereomers.

Actions biochimiques/physiologiques

Anisodamine is a muscarinic receptor antagonist. Anisodamine is a naturally occurring atropine derivative isolated from Scopolia Tangutica Maxim plant indigenous to Tibet.

Anisodamine is a non‐specific cholinergic antagonist. It is considered less efficient and less toxic than atropine. Anisodamine interferes with liposome structure and affects cell membrane. It might act as an anti‐oxidant, in protecting against the damage caused by free radicals. Anisodamine is known to reduce cardiac conduction and also prevents arrhythmia. It can block thromboxane synthesis and might possess anti‐thrombotic function. Anisodamine has been useful in a number therapies including septic shock, circulatory disorders, organophosphorus poisoning, opiate addiction, snake bite and radiation damage. Disorders, such as migraine, gastric ulcers, rheumatoid arthritis, gastrointestinal colic, eclampsia, respiratory diseases, acute glomerular nephritis and obstructive jaundice can be treated with the help of anisodamine.

Caractéristiques et avantages

This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H302,H319
• Conseils de prudence: P264 - P270 - P280 - P301 + P312 - P305 + P351 + P338 - P337 + P313
• Classification des risques: Acute Tox. 4 Oral - Eye Irrit. 2
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable