L1026

Lidocaine

analytical standard

• Synonyme(s) : 2-Diethylamino-N-(2,6-dimethylphenyl)acetamide, Lignocaine, Xylocaine
• Formule empirique (notation de Hill): C₁₄H₂₂N₂O
• Numéro CAS: 137-58-6
• Poids moléculaire : 234.34
• Numéro CE : 205-302-8
• Numéro MDL: MFCD00026733
• Code UNSPSC : 12352200
• ID de substance PubChem : 24896272
• Nomenclature NACRES : NA.77

Propriétés

• Qualité: analytical standard
• Forme: solid
• Conditionnement: vial of 200 mg
• Technique(s): HPLC: suitable; gas chromatography (GC): suitable
• Application(s): forensics and toxicology; pharmaceutical (small molecule)
• Chaîne SMILES: CCN(CC)CC(=O)Nc1c(C)cccc1C
• InChI: 1S/C14H22N2O/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4/h7-9H,5-6,10H2,1-4H3,(H,15,17)
• Clé InChI: NNJVILVZKWQKPM-UHFFFAOYSA-N
• Informations sur le gène: human ... CYP1A2(1544) , SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335) ; rat ... Scnn1a(25122)

Description

Description générale

Lidocaine is an amide anesthetic, which is used to treat ventricular arrhythmias. It lowers cardiac automaticity and myocardial conduction. Lidocaine inhibits the generation and conduction of nerve impulses. It has an anticonvulsant effect.

Application

Lidocaine has been used to examine its effects in inhibiting lymph flow and protection against envenomation. It has also been used to assess its efficacy as an anti-tussive agent.

Actions biochimiques/physiologiques

Na⁺ channel blocker; class IB antiarrhythmic that is rapidly absorbed after parenteral administration.

Conditionnement

Supplied in amber screw-cap vials

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H302
• Conseils de prudence: P264 - P270 - P301 + P312 - P501
• Classification des risques: Acute Tox. 4 Oral
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Faceshields, Gloves