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Key Documents

502-05A

Sigma-Aldrich

Human Bronchial Epithelial Cells: HBEpC, adult

Synonyme(s) :

HBEpC, HBEpC cells

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About This Item

Code UNSPSC :
41106514
Nomenclature NACRES :
NA.81

Source biologique

human bronchi (normal surface epithelium)

Niveau de qualité

100

Conditionnement

pkg of 500,000 cells

Fabricant/nom de marque

Cell Applications, Inc

Mode de croissance

Adherent

Caryotype

2n = 46

Morphologie

epithelial

Technique(s)

cell culture | mammalian: suitable

Maladie(s) pertinente(s)

asthma; autoimmune diseases; cardiovascular diseases

Conditions d'expédition

dry ice

Température de stockage

−196°C

Description générale

Lot specific orders are not able to be placed through the web. Contact your local sales rep for more details.

HBEpC provide an excellent model system to study all aspects of epithelial function and disease, particularly those related to airway viral infections, as well as tissue repair mechanisms, signaling changes and potential treatments relevant to lung injuries, mechanical and oxidative stress, inflammation, pulmonary diseases and smoking.

When grown on inserts and provided with the liquid/air interface, HBEpC can differentiate into a pseudostriated epithelium and serve as a more physiological 3D tissue model for in vitro studies.

Origine de la lignée cellulaire

Bronchi

Application

epithelial function, tissue repair, cell signaling, lung injury treatment, mechanical and oxidative stress tests, cell differentiation, 3D tissue model, cytokine and growth factor production, apoptosis, cell adhesion molecules, cell permeability, pro-inflammatory signaling, viral fusion mechanisms, gene expression, library screening, mucin secretion

Composants

Cell Basal Medium containing 10% FBS & 10% DMSO

Notes préparatoires

  • 1st passage, >500,000 cells in Cell Basal Medium containing 10% FBS & 10% DMSO
  • Can be cultured at least 16 doublings

Procédure de repiquage

Please refer to the HBEpC Culture Protocol.

Clause de non-responsabilité

Ce produit, destiné à la recherche scientifique, est soumis à une réglementation spécifique en France, y compris pour les activités d'importation et d'exportation (Article L 1211-1 alinéa 2 du Code de la Santé Publique). L'acheteur (c'est-à-dire l'utilisateur final) est tenu d'obtenir une autorisation d'importation auprès du Ministère français de la Recherche, mentionné à l'article L1245-5-1 II du Code de la Santé Publique. En commandant ce produit, vous confirmez détenir l'autorisation d'importation requise.

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Anjana A Kulkarni et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 15(7), 2417-2425 (2009-03-26)
There is a lack of prognostic and predictive biomarkers in epithelial ovarian carcinoma, and the targeting of oncogenic signaling pathways has had limited impact on patient survival in this highly heterogeneous disease. The origin licensing machinery, which renders chromosomes competent
Khuloud Bajbouj et al.
International journal of molecular sciences, 22(11) (2021-07-03)
As a therapeutic approach, epigenetic modifiers have the potential to enhance the efficacy of chemotherapeutic agents. Protein arginine methyltransferase 5 (PRMT5), highly expressed in lung adenocarcinoma, was identified to be involved in tumorigenesis. In the current study, we examined the
Matthew Charman et al.
Frontiers in cellular and infection microbiology, 11, 689707-689707 (2021-10-09)
The induction of antiviral effector proteins as part of a homeostatically controlled innate immune response to infection plays a critical role in limiting the propagation and transmission of respiratory pathogens. However, the prolonged induction of this immune response can lead

Protocoles

Human Bronchial Epithelial Cell line

Technical information for working with human bronchial epithelial cell line including thawing, subculturing and cryopreservation.

Human Bronchial Epithelial Cell line

Technical information for working with human bronchial epithelial cell line including thawing, subculturing and cryopreservation.

Human Bronchial Epithelial Cell line

Technical information for working with human bronchial epithelial cell line including thawing, subculturing and cryopreservation.

Human Bronchial Epithelial Cell line

Technical information for working with human bronchial epithelial cell line including thawing, subculturing and cryopreservation.

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