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Merck
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Key Documents

30906

Sigma-Aldrich

Castor Oil, Ethoxylated

Synonyme(s) :

Cremophor® ELP, ELP, PEG-35 castor oil, Polyoxyl-35 castor oil

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About This Item

Numéro CAS:
61791-12-6
Numéro MDL:
MFCD00130879
Code UNSPSC :
12161900
Nomenclature NACRES :
NA.25

Description

non-ionic

Forme

paste

Impuretés

alkalinity, complies
≤ acetic acid (≤0.5 g/100g (%) verfied on random samples only)
≤0.1% oleic acid
≤0.1% palmitic acid
≤0.2% sulfated ash (verfied on random samples only)
≤0.20% ricinoleic acid
≤0.5% water
≤1 ppm ethylene oxide (verfied on random samples only)
≤1.0% free fatty acids
≤10 ppm dioxan (verfied on random samples only)
≤10 ppm heavy metals (verfied on random samples only)
≤620 ppm diethylene glycol (verfied on random samples only)
≤620 ppm ethylene glycol (verfied on random samples only)

Résidus de calcination

≤0.2%

pH

5.0-7.0 (1 g/10 mL in H2O)

Viscosité

600-750 mPa.s(25 °C)

Indice d'acide

≤2.0 mg KOH/g

Indice d'hydroxyle

65‑78 mg KOH/g

Indice d'iode

25‑35 g/100g

Indice de saponification

65‑70 mg KOH/g

Traces de cations

K: ≤15 ppm

InChI

1S/C4H7Cl2NO2/c5-1-3(2-6)9-4(7)8/h3H,1-2H2,(H2,7,8)

Clé InChI

JMNCUXPHXKHBPY-UHFFFAOYSA-N

Application

Castor Oil, Ethoxylated is used to emulsify and solubilize oils and other water-insoluble substances. Similar to Castor Oil, Ethoxylated but with lower water content and differences in viscosity.

Remarque sur l'analyse

relative density D (25/25) 1.05-1.06

Informations légales

Cremophor is a registered trademark of BASF SE

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

494.6 °F - Not applicable

Point d'éclair (°C)

257 °C - Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

K Itoh et al.
International journal of pharmaceutics, 246(1-2), 75-83 (2002-09-25)
The optimized formulation of N-4472, N-[2-(3,5-di-tert-butyl-4-hydroxyphenethyl)-4,6-difluorophenyl]-N'-[4-(N-benzylpiperidyl)] urea, which was a poorly water-soluble drug, was developed by utilizing the complexation between N-4472 and L-ascorbic acid (VC). It was found that the formulation with Gelucire((R)) 44/14, HCO-60((R)) and sodium dodecyl sulfate provided
Allergic contact dermatitis to polyethylene glycol-7 hydrogenated castor oil.
M Kalavala et al.
Contact dermatitis, 56(5), 287-288 (2007-04-20)
Eiki Goto et al.
Ophthalmology, 109(11), 2030-2035 (2002-11-05)
We developed low-concentration homogenized castor oil eye drops for the treatment of patients with noninflamed obstructive meibomian gland dysfunction (MGD), a major cause of lipid-deficiency dry eye, and assessed the safety, stability, and efficacy of the eye drops. Randomized, double-masked
Nuhad K Ibrahim et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 8(5), 1038-1044 (2002-05-15)
ABI-007 is a novel Cremophor-free, protein-stabilized, nanoparticle formulation of paclitaxel. The absence of Cremophor EL may permit ABI-007 to be administered without the premedications used routinely for the prevention of hypersensitivity reactions. Furthermore, this novel formulation permits a higher paclitaxel
Yukako Ito et al.
Journal of drug targeting, 13(6), 383-390 (2005-11-10)
Interferon alpha (IFN-alpha), patch preparations composed of three layers, water-insoluble backing layer, drug containing layer with absorption enhancer and surface layer containing pH-dependent polymer were prepared. As absorption enhancer, three surfactants, Gelucire44/14 (Lauroyl macrogol-32 glycerides), Labrasol (Caprylocaproyl macrogol-8 glycerides) and
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