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Key Documents

200R-1

Sigma-Aldrich

Androgen Receptor (SP107) Rabbit Monoclonal Antibody

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About This Item

Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Niveau de qualité

100
500

Conjugué

unconjugated

Forme d'anticorps

culture supernatant

Type de produit anticorps

primary antibodies

Clone

SP107, monoclonal

Description

For In Vitro Diagnostic Use in Select Regions (See Chart)

Forme

buffered aqueous solution

Espèces réactives

human

Conditionnement

vial of 0.1 mL concentrate (200R-14)
vial of 0.5 mL concentrate (200R-15)
bottle of 1.0 mL predilute (200R-17)
vial of 1.0 mL concentrate (200R-16)
bottle of 7.0 mL predilute (200R-18)

Fabricant/nom de marque

Cell Marque

Technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200

Isotype

IgG

Contrôle

prostate

Conditions d'expédition

wet ice

Température de stockage

2-8°C

Visualisation

nuclear

Description générale

As a member of the steroid hormone superfamily, androgen receptor functions within distinctintracellular compartments to mediate cellular growth and transcriptional activation ofandrogen-regulated signaling pathways. Androgen receptor expression is broadly distributedacross a variety of normal tissue types. The anti-androgen receptor may be used as an aid toidentify carcinomas of the breast and prostate.

Qualité


IVD

IVD

IVD

RUO

Liaison

Androgen Receptor Positive Control Slides, Product No. 200S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Forme physique

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Notes préparatoires

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Autres remarques

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Informations légales

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

A K Roy et al.
Annals of the New York Academy of Sciences, 949, 44-57 (2002-01-25)
Androgens are C-19 steroids secreted primarily from the testes and adrenals that play a critical role in reproduction. Reproductive functions of androgens are mediated through coordination of diverse physiological processes ranging from brain functions to specific cell proliferation and apoptosis.
Laura C Collins et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 24(7), 924-931 (2011-05-10)
Previous studies have demonstrated that androgen receptor is expressed in many breast cancers, but its expression in relation to the various breast cancer subtypes as defined by molecular profiling has not been studied in detail. We constructed tissue microarrays from
Claire Bléchet et al.
Virchows Archiv : an international journal of pathology, 450(4), 433-439 (2007-03-03)
Previous studies have shown that C cells are twice as numerous in male than in female thyroids and that C cell hyperplasia (CCH) is much more frequent in men. These findings suggest regulation involving sex steroid hormones through the expression
L O Gonzalez et al.
Histopathology, 50(7), 866-874 (2007-06-05)
To evaluate the expression of androgen receptors (AR) and two androgen-induced proteins [apolipoprotein D (ApoD) and pepsinogen C (PepC)] in ductal carcinoma in situ (DCIS) of the breast. AR, ApoD and PepC expression was examined in 28 cases of pure
J M Hakimi et al.
World journal of urology, 14(5), 329-337 (1996-01-01)
Androgen-receptor (AR) gene mutations have been found in clinical prostate cancer, both prior to hormonal therapy and in hormone-refractory disease that persists despite androgen-ablative therapy. Thus, mutations that are present in late-stage disease might arise prior to therapy rather than

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