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Y0000017

Propofol for peak identification

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

2,6-Diisopropylphenol, 2,6-Bis(1-methylethyl)phenol, 2,6-Bis(isopropyl)phenol, Propofol

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About This Item

Formule linéaire :
[(CH3)2CH]2C6H3OH
Numéro CAS:
2078-54-8
Poids moléculaire :
178.27
Numéro MDL:
MFCD00008885
Code UNSPSC :
41116107
ID de substance PubChem :
329830816
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Pression de vapeur

5.6 mmHg ( 100 °C)

Famille d'API

propofol

Fabricant/nom de marque

EDQM

Indice de réfraction

n20/D 1.514 (lit.)

Point d'ébullition

256 °C/764 mmHg (lit.)

Pf

18 °C (lit.)

Densité

0.962 g/mL at 25 °C (lit.)

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

CC(C)c1cccc(C(C)C)c1O

InChI

1S/C12H18O/c1-8(2)10-6-5-7-11(9(3)4)12(10)13/h5-9,13H,1-4H3

Clé InChI

OLBCVFGFOZPWHH-UHFFFAOYSA-N

Informations sur le gène

human ... GABRA1(2554) , GABRA2(2555) , GABRA3(2556) , GABRA4(2557) , GABRA5(2558) , GABRA6(2559) , GABRB1(2560) , GABRB2(2561) , GABRB3(2562) , GABRD(2563) , GABRE(2564) , GABRG1(2565) , GABRG2(2566) , GABRG3(2567) , GABRP(2568) , GABRQ(55879)

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Catégories apparentées

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Propofol for peak identification EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

Y0000016

Propofol, European Pharmacopoeia (EP) Reference Standard

Y0000018

Propofol impurity J, European Pharmacopoeia (EP) Reference Standard

1572503

Propofol, United States Pharmacopeia (USP) Reference Standard

1572547

Propofol Related Compound B, United States Pharmacopeia (USP) Reference Standard

1572525

Propofol Resolution Mixture, United States Pharmacopeia (USP) Reference Standard

1572558

Propofol Related Compound C, United States Pharmacopeia (USP) Reference Standard

1572536

Propofol Related Compound A, United States Pharmacopeia (USP) Reference Standard

PHR1663

Propofol, Pharmaceutical Secondary Standard; Certified Reference Material

BP1031

Propofol, British Pharmacopoeia (BP) Reference Standard

BP698

3,3′-5,5′-Tetraisopropyldiphenol, British Pharmacopoeia (BP) Reference Standard

BP1032

Propofol impurity J, British Pharmacopoeia (BP) Reference Standard

PHR9035

4-Isopropylphenol, reference material

PHR9049

4-Hydroxy-3,5-bis(1-methylethyl)benzoic acid, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

PHR9062

1-(1-Methylethoxy)-2-(1-methylethyl)benzene, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

PHR9074

2,2-Dimethyl-4-(1-methylethyl)-1,3-benzodioxole, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

PHR2565

Propofol Related Compound A, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2566

Propofol Related Compound B

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H302,H315,H319,H335

Classification des risques

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

235.4 °F - closed cup

Point d'éclair (°C)

113 °C - closed cup

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Certificats d'analyse (COA)

Lot/Batch Number

Désolés, nous n'avons pas de COA pour ce produit disponible en ligne pour le moment.

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Muhammad Suleman Khan et al.
Basic & clinical pharmacology & toxicology, 115(6), 565-570 (2014-06-04)
A variety of techniques have been developed to monitor the depth of anaesthesia. Propofol's pharmacokinetics and response vary greatly, which might be explained by genetic polymorphisms. We investigated the impact of genetic variations on dosage, anaesthetic depth and recovery after
Cynthia Ménard et al.
Radiology, 274(1), 181-191 (2014-09-10)
To determine if the integration of diagnostic magnetic resonance (MR) imaging and MR-guided biopsy would improve target delineation for focal salvage therapy in men with prostate cancer. Between September 2008 and March 2011, 30 men with biochemical failure after radiation
Christine Happle et al.
Science translational medicine, 6(250), 250ra113-250ra113 (2014-08-22)
Hereditary pulmonary alveolar proteinosis (herPAP) is a rare lung disease caused by mutations in the granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor genes, resulting in disturbed alveolar macrophage differentiation, massive alveolar proteinosis, and life-threatening respiratory insufficiency. So far, the only effective treatment
Philippe E Dubois et al.
European journal of anaesthesiology, 31(8), 404-410 (2013-07-26)
Disturbances in the thumb's movement interfere with the functioning of acceleromyography in many clinical settings. The short and light (SL) train-of-four (TOF)-Tube is a new version of a rigid tubular device that was designed to protect the thumb from external
Eran A Mukamel et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(3), 839-845 (2014-01-17)
Rhythmic oscillations shape cortical dynamics during active behavior, sleep, and general anesthesia. Cross-frequency phase-amplitude coupling is a prominent feature of cortical oscillations, but its role in organizing conscious and unconscious brain states is poorly understood. Using high-density EEG and intracranial
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