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STS0204

Sigma-Aldrich

TWEEN® 80

greener alternative

viscous liquid

Synonyme(s) :

Mono-oléate de polyoxy-éthylènesorbitane, Mono-oléate de polyéthylène glycol sorbitane, Monooléate de POE (20)-sorbitane, Polysorbate 80

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About This Item

Numéro CAS:
Numéro MDL:
Code UNSPSC :
12161902
Nomenclature NACRES :
NA.28

Description

non-ionic

Niveau de qualité

Pureté

≥58%

Forme

viscous liquid

Poids mol.

micellar avg mol wt 79.000
average mol wt 1310

Composition

Oleic acid, ≥58.0% (balance primarily linoleic, palmitic, and stearic acids)

Caractéristiques du produit alternatif plus écologique

Use of Renewable Feedstocks
Design for Degradation
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

CMC

0.012 mM (20-25°C)

Viscosité

300—500 cP(25 °C)

Température de transition

cloud point 65 °C

Solubilité

water: 100 mg/mL, clear to slightly hazy, faintly yellow

Densité

1.064 g/cm3

HLB

15.0

Autre catégorie plus écologique

Chaîne SMILES 

CCCCCCCC/C=C/CCCCCCCC(=O)OCCOCC(C1C(CC(O1)OCCO)OCCO)OCCO

InChI

1S/C32H60O10/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-30(36)40-25-24-37-27-29(39-22-19-34)32-28(38-21-18-33)26-31(42-32)41-23-20-35/h9-10,28-29,31-35H,2-8,11-27H2,1H3/b10-9+

Clé InChI

RGPBUVUVZKQNHD-MDZDMXLPSA-N

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Description générale

ECO Tween® 80, also known as Polyoxyethylenesorbitan monooleate, is a bio-based, nonionic detergent manufactured from a natural fatty acid. This surfactant, derived from natural sources, provides various functional advantages, such as detergency, emulsification, and wetting. Its versatility makes it well-suited for a variety of applications in biochemical and biological research, with common uses including cell lysis, protein extraction, nuclei isolation and cell fractionation.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. This product is a biobased surfactant and is aligned with the 7th principle of Green Chemistry "Use of Renewable Feedstocks" and the 10th principle "Design for Degradation".

Application

Non-ionic detergent used for selective protein extraction and isolation of nuclei from mammalian cell lines.
TWEEN® 80 has been used in drug vehicle solution for specific injections in mice and rats. It has been used for the determination of esterase activity in bacterial cells.

Actions biochimiques/physiologiques

TWEEN® 80 is a polysorbate surfactant which helps in stabilizing proteins and in protein membrane studies. It is regularly used for the extraction of membrane proteins and isolation of nuclei from cells.

Caractéristiques et avantages

  • 100 % Renewable
  • 100 % Bio-based
  • Certified to the USDA BioPreferred Program
  • Lower carbon footprint than petrochemical-based versions
  • High-purity chemical suitable for a wide variety of research applications

Autres remarques

For additional information on our range of Biochemicals, please complete this form.

Informations légales

ECO TWEEN is a registered trademark of Croda Inc.
TWEEN is a registered trademark of Croda International PLC

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

>235.4 °F - closed cup

Point d'éclair (°C)

> 113 °C - closed cup


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Consulter la Bibliothèque de documents

V Ryu et al.
Neuroscience, 167(4), 1227-1238 (2010-03-04)
Previous reports show that vagal afferent innervation of the stomach eventually regenerates from surviving nodose ganglion (NG) neurons after subdiaphragmatic vagotomy. Systemic capsaicin treatment destroys gastric vagal afferent neurons expressing vanilloid receptor 1 (VR1). However, it is not known whether
HU-210 shows higher efficacy and potency than morphine after intrathecal administration in the mouse formalin test.
Guhring H et al.
European Journal of Pharmacology, 429, 127-127 (2001)
Pathogenic factors of Pseudomonas cepacia isolates from patients with cystic fibrosis.
Gessner AR and Mortensen JE
Journal of Medical Microbiology, 33, 115-115 (1990)
Scopes RK
Protein Purification: Principles and Practice (1993)
Davidson JN
The Biochemistry of the Nucleic Acids (2012)

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