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K2000000

Ketoprofen

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

2-(3-Benzoylphenyl)propionic acid

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About This Item

Formule empirique (notation de Hill):
C16H14O3
Numéro CAS:
22071-15-4
Poids moléculaire :
254.28
Numéro MDL:
MFCD00055790
Code UNSPSC :
41116107
ID de substance PubChem :
329817130
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

ketoprofen

Fabricant/nom de marque

EDQM

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable

Application(s)

pharmaceutical (small molecule)

Format

neat

Chaîne SMILES 

CC(C(O)=O)c1cccc(c1)C(=O)c2ccccc2

InChI

1S/C16H14O3/c1-11(16(18)19)13-8-5-9-14(10-13)15(17)12-6-3-2-4-7-12/h2-11H,1H3,(H,18,19)

Clé InChI

DKYWVDODHFEZIM-UHFFFAOYSA-N

Informations sur le gène

human ... PTGS1(5742) , PTGS2(5743)

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Catégories apparentées

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Ketoprofen EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Actions biochimiques/physiologiques

Composé anti-inflammatoire non stéroïdien spécifique de la COX-1.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

1356632

Ketoprofen, United States Pharmacopeia (USP) Reference Standard

K2000010

Ketoprofen impurity A, European Pharmacopoeia (EP) Reference Standard

K2000015

Ketoprofen impurity C, European Pharmacopoeia (EP) Reference Standard

1356643

Ketoprofen Related Compound A, United States Pharmacopeia (USP) Reference Standard

1356563

Ketoprofen Related Compound D hydrochloride, United States Pharmacopeia (USP) Reference Standard

1356552

Ketoprofen Related Compound C, United States Pharmacopeia (USP) Reference Standard

BP668

Ketoprofen, British Pharmacopoeia (BP) Reference Standard

BP667

Ketoprofen ethyl ester, British Pharmacopoeia (BP) Reference Standard

PHR2877

Ketoprofen Related Compound F, pharmaceutical secondary standard, certified reference material

PHR2955

Ketoprofen Related Compound D, pharmaceutical secondary standard, certified reference material

PHR3018

Ketoprofen Related Compound C, pharmaceutical secondary standard, certified reference material

Pictogrammes

Skull and crossbonesEnvironment
GHS06,GHS09

Mention d'avertissement

Danger

Mentions de danger

H301,H315,H319,H400

Classification des risques

Acute Tox. 3 Oral - Aquatic Acute 1 - Eye Irrit. 2 - Skin Irrit. 2

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

Désolés, nous n'avons pas de COA pour ce produit disponible en ligne pour le moment.

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Ikram Ullah Khan et al.
International journal of pharmaceutics, 441(1-2), 809-817 (2012-12-26)
Microchannels based microfluidic systems are able to obtain monodispersed microparticles but are limited by cost, time and channel clogging. We succeeded in on the fly encapsulation of high ketoprofen contents in acrylate-based copolymer microbeads by environment friendly UV induced free
Yan-Ping Duan et al.
The Science of the total environment, 447, 267-273 (2013-02-09)
The occurrence and multi-phase distribution of five pharmaceutical compounds were investigated in an urban wastewater treatment plant (WWTP) receiving river by analysis of pharmaceuticals in sediment, particulate matter, conventional dissolved phase (>0.7 μm), colloidal phase (5 kDa to 0.7 μm)
Zeting Yuan et al.
International journal of pharmaceutics, 446(1-2), 191-198 (2013-02-21)
Chitosan (CS) grafted with β-cyclodextrin (CD-g-CS) nanoparticles as a new carrier for poorly water-soluble drugs has been developed. The CD-g-CS polymer is readily synthesized from chitosan and mono-6-deoxy-6-(p-toluenesulfonyl)-β-cyclodextrin. Three different degrees of substitution (DS) of β-cyclodextrin (β-CD) on CD-g-CS (9.6
F Jamali et al.
Clinical pharmacokinetics, 19(3), 197-217 (1990-09-01)
Ketoprofen, a potent nonsteroidal anti-inflammatory drug (NSAID) of the 2-arylpropionic acid class, has been used clinically for over 15 years in Europe, and has recently been introduced in the United States. Although it possesses a chiral centre, with only the
H Bagheri et al.
Drug safety, 22(5), 339-349 (2000-06-01)
The topical use of nonsteroidal anti-inflammatory drugs (NSAIDs), widely used for moderate acute and chronic painful conditions, is one of several strategies used to improve the tolerability profile of NSAIDs, particularly with regard to gastric and renal adverse effects. However
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