The solubility of this product is not determined. However, literature indicates that gamithromycin is typically soluble in DMSO. The exact concentration at which it can be solubilized is not determined.
32161
Gamithromycin
VETRANAL®, analytical standard
Synonyme(s) :
(2R,3S,4R,5S,8RR,10R,11R,12S,13S,14R)-13-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-7-propyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylohexopyranosyl]oxy]-1-oxa-7-azacyclopentadecan-15-one
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About This Item
Formule empirique (notation de Hill):
C40H76N2O12
Numéro CAS:
Poids moléculaire :
777.04
Numéro MDL:
Code UNSPSC :
41116107
Nomenclature NACRES :
NA.24
Le tarif et la disponibilité ne sont pas disponibles actuellement.
Produits recommandés
Qualité
analytical standard
Niveau de qualité
Gamme de produits
VETRANAL®
Technique(s)
HPLC: suitable
gas chromatography (GC): suitable
Application(s)
forensics and toxicology
veterinary
Format
neat
Température de stockage
2-8°C
Chaîne SMILES
N1([C@@H](C[C@]([C@@H](C([C@@H]([C@H](C(=O)O[C@@H]([C@]([C@@H]([C@H](C1)C)O)(O)C)CC)C)O[C@@H]3O[C@H]([C@@H]([C@@](C3)(OC)C)O)C)C)O[C@@H]2O[C@@H](C[C@@H]([C@H]2O)N(C)C)C)(O)C)C)CCC
InChI
1S/C40H76N2O12/c1-15-17-42-21-22(3)33(44)40(11,48)29(16-2)52-36(46)26(7)32(53-30-20-39(10,49-14)34(45)27(8)51-30)25(6)35(38(9,47)19-23(42)4)54-37-31(43)28(41(12)13)18-24(5)50-37/h22-35,37,43-45,47-48H,15-21H2,1-14H3/t22-,23+,24+,25?,26+,27-,28-,29+,30-,31+,32-,33+,34-,35+,37-,38+,39+,40+/m0/s1
Clé InChI
VWAMTBXLZPEDQO-FWEXOAGLSA-N
Catégories apparentées
Description générale
Application
Gamithromycin may be used as a reference standard in the determination of gamithromycin in samples of plasma, lung tissue and pulmonary epithelial lining fluid using liquid chromatography coupled with tandem mass spectrometry (LC-MS-MS).[2]
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Informations légales
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
Mention d'avertissement
Warning
Mentions de danger
Conseils de prudence
Classification des risques
Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
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Journal of animal science, 96(3), 890-901 (2018-02-01)
Crossbred beef bulls (n = 180) were blocked by initial BW (337 ± 10.9 kg; six blocks) and assigned randomly to one of three treatments on day 0: 1) INJ; received 1 mL (100 mg Zn) of a Zn solution
Michael Kellermann et al.
Research in veterinary science, 97(2), 199-203 (2014-09-23)
This study assessed the plasma kinetics and skin/plasma concentration ratio of the azalide antibiotic gamithromycin (ZACTRAN(®), Merial) in sheep after a single subcutaneous administration at 6 mg/kg bodyweight. Gamithromycin concentrations in plasma samples collected at various intervals up to 21
Michal Beker et al.
Frontiers in microbiology, 9, 1329-1329 (2018-07-13)
Strains of the Pasteurellaceae bacteria Pasteurella multocida and Mannheimia haemolytica are major etiological agents of bovine respiratory disease (BRD). Treatment of BRD with antimicrobials is becoming more challenging due to the increasing occurrence of resistance in infecting strains. In Pasteurellaceae
Development and validation of a liquid chromatography?tandem mass spectrometry method for the quantitative determination of gamithromycin in animal plasma, lung tissue and pulmonary epithelial lining fluid.
Baere DS, et al.
Journal of Chromatography A, 1398, 73-82 (2015)
Saunders Handbook of Veterinary Drugs: Small and Large Animal (2015)
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I would like to know about the solubility of gamithromycin. in which solvent is it recommended to be solubilized and at what maximum concentration?
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