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MAB5416

Sigma-Aldrich

Anti-Glutamate Receptor 3 Antibody, clone 3B3

clone 3B3, Chemicon®, from mouse

Synonyme(s) :

AMPA-selective glutamate receptor 3, Glutamate receptor ionotropic, AMPA 3, glutamate receptor 3, glutamate receptor C, glutamate receptor subunit 3, glutamate receptor, ionotrophic, AMPA 3

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

mouse

Niveau de qualité

100

Forme d'anticorps

purified antibody

Type de produit anticorps

primary antibodies

Clone

3B3, monoclonal

Espèces réactives

monkey, mouse, human

Réactivité de l'espèce (prédite par homologie)

rat

Fabricant/nom de marque

Chemicon®

Technique(s)

immunocytochemistry: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
western blot: suitable

Isotype

IgG1κ

Numéro d'accès NCBI

NM_000840.2

Numéro d'accès UniProt

P42263

Conditions d'expédition

dry ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... GRIA3(2892)

Description générale

AMPA receptors mediate fast synaptic current at most excitatory synapses, with stoichiometry characterized by subtype composition.There are four types of AMPA selective GluR subunits (GluR1, GluR2, GluR3 and GluR4). Tetrameric or pentameric combinations of different subunits contributes to the functional diversity of AMPA receptors. The insertion or removal of GluR1/GluR4 oligomeric channels from postsynaptic membranes appears to be LTP/LTD activity dependent while GluR2/GluR3 oligomers are continuously cycling. Millipore’s anti-GluR2/3 antibody is useful for localizing expression of GluR2/GluR3 receptor assemblies in the PSD.

Spécificité

Reacts with Glutamate Receptor 3 (GluR3). No cross reactivity with GluR2.

Immunogène

Fusion protein, N-terminus of GluR3

Application

Anti-Glutamate Receptor 3 Antibody, clone 3B3 is an antibody against Glutamate Receptor 3 for use in WB, IC, IH, IH(P).
Immunohistochemistry: A previous lot of this antibody was used in IH.

Optimal working dilutions must be determined by end user.

Qualité

Western Blot Analysis: A previous lot of this antibody was used in WB.

Description de la cible

~ 110 kDa

Forme physique

Format: Purified
Liquid in PBS. Contains no preservative.

Remarque sur l'analyse

Control
Brain

Hippocampal tissue

Autres remarques

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Informations légales

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

David Bartolomé-Martín et al.
Journal of cell science, 125(Pt 2), 422-434 (2012-02-15)
Following the exocytosis of neurotransmitter-containing synaptic vesicles, endocytosis is fundamental to re-establishing conditions for synaptic transmission. As there are distinct endocytotic pathways that each differ in their efficiency to generate releasable synaptic vesicles, we used the dye FM1-43 to track
Evolutionarily conserved pattern of AMPA receptor subunit glycosylation in Mammalian frontal cortex.
Tucholski, J; Pinner, AL; Simmons, MS; Meador-Woodruff, JH
Testing null
Janusz Tucholski et al.
Schizophrenia research, 146(1-3), 177-183 (2013-03-07)
Numerous studies have demonstrated brain region- and subunit-specific abnormalities in the expression of subunits of the AMPA subtype of glutamate receptors in schizophrenia. In addition, abnormalities in the expression of proteins that regulate the forward trafficking of AMPA receptors through
Sven Jarius et al.
Journal of neuroinflammation, 11, 206-206 (2014-12-17)
We report on a serum autoantibody associated with cerebellar ataxia. Immunohistochemical studies of sera from four patients referred for autoantibody testing revealed binding of high-titer (up to 1:5,000) IgG antibodies, mainly IgG1, to the molecular layer, Purkinje cell layer, and
Myung-Su Kang et al.
The Journal of experimental medicine, 214(10), 2947-2966 (2017-09-14)
Vaccinia-related kinases (VRKs) are multifaceted serine/threonine kinases that play essential roles in various aspects of cell signaling, cell cycle progression, apoptosis, and neuronal development and differentiation. However, the neuronal function of VRK3 is still unknown despite its etiological potential in
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