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Key Documents

MAB3307

Sigma-Aldrich

Anti-MMP-1 Antibody, a.a. 332-350 hMMP1, clone 41-1E5

clone 41-1E5, Chemicon®, from mouse

Synonyme(s) :

Fibroblast Collagenase, Interstitial Collagenase

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

mouse

Niveau de qualité

100

Forme d'anticorps

purified immunoglobulin

Type de produit anticorps

primary antibodies

Clone

41-1E5, monoclonal

Espèces réactives

rabbit, human

Fabricant/nom de marque

Chemicon®

Technique(s)

ELISA: suitable
immunohistochemistry: suitable (paraffin)
western blot: suitable

Isotype

IgG2aκ

Numéro d'accès NCBI

NM_002421.2

Numéro d'accès UniProt

P03956

Conditions d'expédition

dry ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... MMP1(4312)

Spécificité

Specifically reacts with precursor and active forms of human MMP-1.

Immunogène

Epitope: a.a. 332-350 hMMP1
Syntheic peptide aa332-350 of hMMP-1

Application

Anti-MMP-1 Antibody, a.a. 332-350 hMMP1, clone 41-1E5 detects level of MMP-1 & has been published & validated for use in ELISA, IH(P) & WB.
Immunoblotting:

Immunohistochemistry on PLP fixed, paraffin-embedded tissues 5-20μg/ml. PLP fixation required for best results. Antibody also reacts with frozen tissues. Reactivity on tradional formalin fixed tissue is poor. Microwave antigen retrieval is recommended

ElA

Description de la cible

52 kDa

Liaison

Replaces: 04-1122

Forme physique

Format: Purified
Liquid in 0.1 M Na-Phosphate buffer, pH 7.0 containing 2% protease free bovine Serum albumin.

Remarque sur l'analyse

Control
Cervical carcinoma

SKBr-3 cell lysate

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informations légales

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Satoru Kondo et al.
International journal of cancer, 115(3), 368-376 (2005-02-03)
The Epstein-Barr Virus (EBV) latent membrane protein 1 (LMP1) has a significant role in several malignancies, including nasopharyngeal carcinoma (NPC). LMP1 is the principal oncoprotein, and we have shown that it also induces a set of factors that mediates invasion
Angela Ghatnekar et al.
The American journal of pathology, 182(6), 2391-2406 (2013-04-16)
Pulmonary arterial hypertension (PAH) is a chronic and progressive disease characterized by pulmonary vasculopathy with elevation of pulmonary artery pressure, often culminating in right ventricular failure. GATA-6, a member of the GATA family of zinc-finger transcription factors, is highly expressed
Carine Strup-Perrot et al.
World journal of gastroenterology, 11(40), 6312-6321 (2006-01-19)
To investigate their expression and activity in the rat ileum after exposure to ionizing radiation along with that of the cellular effectors and molecular mediators involved in the regulation of MMPs. Rats were exposed to a single 10-Gy dose of
Jangyoun Choi et al.
International wound journal, 18(5), 647-656 (2021-03-19)
A hypertrophic scar is a common dermal fibroproliferative lesion usually treated with topical silicone. Verapamil, a type of calcium channel blocker, is considered a candidate drug for the treatment of hypertrophic scars. Here, we report that the addition of verapamil
Marc Irqsusi et al.
Journal of cardiac surgery, 37(6), 1613-1622 (2022-03-29)
The pathogenesis of mitral valve insufficiency is not yet fully understood. Several studies stressed the role of matrix metalloproteinases (MMPs) in the emergence of valvular pathologies. The primary objective of the present study is to analyze the role of selected MMPs
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