AB3402P

Anti-Agouti Related Protein Antibody

Chemicon^®, from rabbit

• Synonyme(s) : AGRP
• Code UNSPSC : 12352203
• eCl@ss : 32160702
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Forme d'anticorps: affinity purified immunoglobulin
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Produit purifié par: affinity chromatography
• Espèces réactives: mouse
• Fabricant/nom de marque: Chemicon^®
• Technique(s): ELISA: suitable; western blot: suitable
• Numéro d'accès NCBI: NM_001138.1; NM_007316.1
• Numéro d'accès UniProt: O00253
• Conditions d'expédition: dry ice
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... AGRP(181)

Description

Description générale

Agouti-related peptide-expressing (AgRP) neurons seem to be critical for the acute regulation of eating. The AgRP protein is a strong antagonis of MC3-R and MC4-R and is expressed primarily in the adrenal gland, subthalamic nucleus, and hypothalamus, with a lower level of expression occurring in testis, lung, and kidney.

Spécificité

Recognizes AGRP. The immunogen shows no significant sequence homology with Agouti, tubby, tub, TULP1 or TULP2.

SPECIES REACTIVITIES: The immunogen sequence is 85% homologous with human and bovine. Reactivity with other species has not been confirmed.

Immunogène

A 15 amino acid peptide near the C-terminus of mouse AGRP (Shutter et al. 1997; Ollmann et al. 1997).

Application

Detect Agouti Related Protein using this Anti-Agouti Related Protein Antibody validated for use in ELISA & WB.

Research Category
Metabolism

Research Sub Category
Glucose/Glycogen Metabolism

Western blot: 1-10 μg/mL using ECL.



ELISA: 1:10,000-1:50,000 using 50-100 ng control peptide per well.

Optimal working dilutions must be determined by the end user.

Forme physique

Liquid in phosphate buffered saline containing 0.1% BSA.

Stockage et stabilité

Maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informations légales

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable