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Key Documents

780200P

Avanti

16:0 PE MCC

1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[4-(p-maleimidomethyl)cyclohexane-carboxamide] (sodium salt), powder

Synonyme(s) :

1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine-N-[4-(p-maleimidomethyl)cyclohexane-carboxamide] (sodium salt)

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About This Item

Formule empirique (notation de Hill):
C49H86N2O11PNa
Numéro CAS:
384832-87-5
Poids moléculaire :
933.18
Code UNSPSC :
12352211
Nomenclature NACRES :
NA.25

Pureté

>99% (TLC)

Forme

powder

Conditionnement

pkg of 1 × 25 mg (780200P-25mg)

Fabricant/nom de marque

Avanti Research™ - A Croda Brand 780200P

Conditions d'expédition

dry ice

Température de stockage

−20°C

Description générale

1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[4-(p-maleimidomethyl)cyclohexane-carboxamide] (16:0 PE MCC) is a lipid consisting of phosphoethanolamine linked to two palmitic acid through its phosphate group and to a maleimide group by its amino group. It is a maleimide-functionalized lipid.

Application

16:0 PE MCC (1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[4-(p-maleimidomethyl)cyclohexane-carboxamide]) may been used in functionalized liposome preparation for drug delivery. It may also be used in liposome preparation for testing drug delivery functionality and as a component in microbubble dispersions.

Actions biochimiques/physiologiques

1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[4-(p-maleimidomethyl)cyclohexane-carboxamide](DPPE-MCC) via the maleimide group enables covalent attachment in functionalized liposomes and is useful in peptide transport studies.

Conditionnement

5 mL Amber Glass Screw Cap Vial (780200P-25mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Code de la classe de stockage

11 - Combustible Solids

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Astrid Hilde Myrset et al.
Ultrasound in medicine & biology, 37(1), 136-150 (2010-12-15)
Targeted ultrasound (US) contrast agents represent, because of their size (1 to 5 μm), a unique class of diagnostic imaging agents enabling true vascular imaging of conditions like inflammation and tumor angiogenesis. The objective of this study was to develop
K Gradauer et al.
Journal of controlled release : official journal of the Controlled Release Society, 172(3), 872-878 (2013-10-22)
The aim of the present study was the in vivo evaluation of thiomer-coated liposomes for an oral application of peptides. For this purpose, salmon calcitonin was chosen as a model drug and encapsulated within liposomes. Subsequently, the drug loaded liposomes
K Gradauer et al.
Journal of controlled release : official journal of the Controlled Release Society, 165(3), 207-215 (2012-12-12)
An ideal oral drug carrier should facilitate drug delivery to the gastrointestinal tract and its absorption into the systemic circulation. To meet these requirements, we developed a thiomer-coated liposomal delivery system composed of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) and a maleimide-functionalized lipid, to

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