799041

Poly(ethylene glycol) methyl ether-block-poly(L-lactide-co-glycolide)

PEG average M_n 5,000, PLGA average M_n 25,000, lactide:glycolide 50:50

• Synonyme(s) : PEG-PLGA, PEG-b-PLGA
• Formule linéaire : CH₃[C₂H₄O]_nO[(C₂H₂O₂)_x(C₃H₄O₂)_y]_mH
• Code UNSPSC : 12162002
• Nomenclature NACRES : NA.23

Propriétés

• Forme: powder
• Niveau de qualité: 100
• Poids mol.: PEG average M_n 5,000; PLGA average M_n 25,000
• Composition: lactide:glycolide 50:50
• Température de stockage: 2-8°C

Description

Application

Amphiphilic block copolymers (AmBC) are made up of two chemically different homopolymer blocks. One of the block is hydrophilic and the other one is hydrophobic. These macromolecules have the properties to self-assemble when dissolved in an aqueous media. PEG-PLGA is one the most commonly used biodegradable amphiphilic block copolymers for drug delivery applications. PEG is the hydrophilic part and PLGA is the hydrophobic part.Used in the synthesis of targeted nanoparticles which are used for differential delivery and controlled release of drugs

Caractéristiques et avantages

• Good biocompatibility, low immunogenicity and good degradability.
• Properties can be easily modulated by changing the block copolymer segment sizes to suit a particular application.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable