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765457

Sigma-Aldrich

Gold nanoparticles

10 nm diameter, carboxylic acid functionalized, PEG 3000, OD 50, dispersion in H2O

Synonyme(s) :

Gold nanoparticles COOH functionalized, Au NP COOH, Gold Colloid

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About This Item

Code UNSPSC :
12162002
Nomenclature NACRES :
NA.23

Matériaux

PEG 3000

Forme

dispersion in H2O
nanoparticles

Conditionnement

glass bottle of 1 mL

DO

50

Diamètre

10 nm

pH

6.0-8.0 (25 °C)

Solubilité

water: miscible

Densité

1.00 g/cm3

λmax

520 nm

Groupe fonctionnel

carboxylic acid

Température de stockage

2-8°C

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Description générale

Carboxylic acid functionalized GNPs form conjugates with various protein molecules due to the electrostatic attraction between negatively charged carboxylate groups and positively charged amino groups of protein.

Application

Carboxylic acid functionalized, PEG 3000, OD 50, and H2O dispersed gold nanoparticles (10 nm) (AuNPs) can be potentially used in the development of biosensors, cancer-cell imaging, drug delivery, and photothermal therapy. AUNPs may also be used in the immobilization of antibodies to improve the sensitivity of optical fiber sensors for the screening of COVID-19. It can also be deposited on the titanium electrode for the formation of a miniaturized device for the electrochemical detection of DNA hybridization.
The carboxylic acid group binds with various proteins and is used in targeted drug delivery and gene therapy.
Functionalized Particles have been extensively used to study cellular uptake of nanoparticles and targeted drug delivery.

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Optical Fiber Sensors for Rapid Screening of COVID-19
Nag P, et al.
Transactions of the Indian National Academy of Engineering, 6, 1-4 (2020)
Size-dependent in vivo toxicity of PEG-coated gold nanoparticles
Zhang X, et al.
International journal of nanomedicine, 6, 2071-2071 (2011)
Nishima Wangoo et al.
Journal of colloid and interface science, 323(2), 247-254 (2008-05-20)
We report a novel strategy for the synthesis of aqueous stable, carboxylated gold nanoparticles (GNPs) by using glutamic acid as the reducing agent. The ratio of chloroaurate ions, AuCl(-)(4) to glutamic acid was optimized in the reaction medium to obtain
Functionalized gold nanoparticles and their biomedical applications
Tiwari, P. M., Vig, K., Dennis, V. A., & Singh, S. R.
Nanomaterials, 1(1), 31-63 (2011)

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Magnetic Nanoparticles for Cancer Theranostics

The recent emergence of a number of highly functional nanomaterials has enabled new approaches to the understanding, diagnosis, and treatment of cancer.

Magnetic Nanoparticles for Cancer Theranostics

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