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406902

Sigma-Aldrich

6-Mercaptopyridine-3-carboxylic acid

technical grade, 90%

Synonyme(s) :

6-Mercaptonicotinic acid

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About This Item

Formule empirique (notation de Hill):
C6H5NO2S
Numéro CAS:
Poids moléculaire :
155.17
Numéro MDL:
Code UNSPSC :
12352100
ID de substance PubChem :
Nomenclature NACRES :
NA.22

Qualité

technical grade

Pureté

90%

Forme

solid

Pf

260-262 °C (dec.) (lit.)

Chaîne SMILES 

OC(=O)c1ccc(S)nc1

InChI

1S/C6H5NO2S/c8-6(9)4-1-2-5(10)7-3-4/h1-3H,(H,7,10)(H,8,9)

Clé InChI

JWWGTYCXARQFOT-UHFFFAOYSA-N

Description générale

6-Mercaptopyridine-3-carboxylic acid (MPCA, 6-mercaptonicotinic acid, MNA) is a bifunctional ligand, made up of pyridine moiety containing carboxylic and mercapto group. The electrochemical properties of self-assembled monolayers (SAMs) of MNA on gold electrode have been described.

Application

6-Mercaptopyridine-3-carboxylic acid may be used in the following processes:
  • Fabrication of nanowell based sensors for the detection of improvised explosive devices (IEDs).
  • Functionalization of gold nanoparticles (AuNPs) for the highly sensitive and selective detection of Cd2+ in colorimetric assay.
  • Preparation of thiolated chitosans, which are thiolated biopolymers exhibiting mucoadhesive, enzyme inhibitory, and permeation enhancing properties.
  • Synthesis of Zinc(II) coordination polymers.

Pictogrammes

Exclamation mark

Mention d'avertissement

Warning

Mentions de danger

Classification des risques

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves


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Consulter la Bibliothèque de documents

Highly sensitive and specific determination of mercury (II) ion in water, food and cosmetic samples with an ELISA based on a novel monoclonal antibody.
Wang Y, et al.
Analytical and Bioanalytical Chemistry, 403(9), 2519-2528 (2012)
Pei She et al.
Analytica chimica acta, 906, 139-147 (2016-01-17)
An immunochromatographic test (ICT) strip was developed for ultrasensitive competitive immunoassay of Hg(2+). This strategy was achieved by combining the easy-operation and rapidity of ICT with the high sensitivity of surface-enhanced Raman scattering (SERS). Monoclonal antibody (mAb) against Hg(2+) and
Ying Xue et al.
The Analyst, 136(18), 3725-3730 (2011-08-02)
We have developed a colorimetric assay for the highly sensitive and selective detection of Cd(2+) using gold nanoparticles (AuNPs) cofunctionalized with 6-mercaptonicotinic acid (MNA) and L-Cysteine (L-Cys) through the formation of an Au-S bond. In the presence of Cd(2+), the
Gioconda Millotti et al.
Biomacromolecules, 10(11), 3023-3027 (2009-10-14)
Thiolated chitosans are relatively new thiolated biopolymers exhibiting mucoadhesive, enzyme inhibitory, and permeation enhancing properties. A drawback, however, is their pH dependent reactivity. The aim of this study was therefore to develop a novel thiolated chitosan showing a non pH
A novel two-dimensional zinc (II) coordination polymer with 6-mercaptonicotinic acid.
Wang Y, et al.
Acta Crystallographica Section C, Crystal Structure Communications, 64(1), 70-72 (2008)

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