Determination of volatile organic compounds including alcohols in refill fluids and cartridges of electronic cigarettes by headspace solid-phase micro extraction and gas chromatography-mass spectrometry.

Determination of volatile organic compounds including alcohols in refill fluids and cartridges of electronic cigarettes by headspace solid-phase micro extraction and gas chromatography-mass spectrometry.

Analytical and bioanalytical chemistry (2016-11-09)

Hyun-Hee Lim, Ho-Sang Shin

ABSTRACT

An analytical method for the detection of 14 volatile organic compounds (VOCs) was developed to investigate VOCs in refill fluids and cartridges of electronic cigarettes (EC) using headspace solid-phase micro extraction (HS-SPME) coupled with gas chromatography-mass spectrometry (GC-MS). In total, 14 VOCs were identified and quantified in 283 flavored liquids, 21 nicotine liquids, and 12 disposable cartridges. The detected concentration ranges of the VOCs are as follows: benzene (0.008-2.28 mg L

MATERIALS

Product Number

Brand

Product Description

57328-U

Supelco

SPME fiber assembly Divinylbenzene/Carboxen/Polydimethylsiloxane (DVB/CAR/PDMS), needle size 24 ga, for use with manual holder

57301

Supelco

SPME fiber assembly Polydimethylsiloxane (PDMS), d_f 100 μm(PDMS, for use with autosampler, needle size 24 ga

57305

Supelco

SPME fiber assembly polyacrylate (PA), d_f 85 μm(PA, for use with autosampler, needle size 24 ga

504831

Supelco

SPME Portable Field Sampler, coating CAR/PDMS

57318

Supelco

SPME fiber assembly Carboxen/Polydimethylsiloxane (CAR/PDMS), d_f 75 μm(CAR/PDMS, for use with manual holder, needle size 24 ga

57319

Supelco

SPME fiber assembly Carboxen/Polydimethylsiloxane (CAR/PDMS), d_f 75 μm(CAR/PDMS, needle size 24 ga, for use with autosampler

57333-U

Supelco

SPME Sampling Stand, for use with 4 mL vials

57308

Supelco

SPME fiber assembly Polydimethylsiloxane (PDMS), d_f 30 μm(PDMS, needle size 24 ga, for use with manual holder

57309

Supelco

SPME fiber assembly Polydimethylsiloxane (PDMS), d_f 30 μm(PDMS, needle size 24 ga, for use with autosampler

57345-U

Supelco

SPME Fiber Assembly Polydimethylsiloxane/Divinylbenzene (PDMS/DVB), d_f 65 μm(PDMS/DVB, for use with autosampler, needle size 23 ga

504823

Supelco

SPME Portable Field Sampler, coating PDMS

57302

Supelco

SPME fiber assembly Polydimethylsiloxane (PDMS), d_f 7 μm(PDMS, needle size 24 ga, for use with manual holder

57327-U

Supelco

SPME Fiber Assembly Polydimethylsiloxane/Divinylbenzene (PDMS/DVB), d_f 65 μm(PDMS/DVB, needle size 24 ga, StableFlex, for use with autosampler

57303

Supelco

SPME fiber assembly Polydimethylsiloxane (PDMS), d_f 7 μm(PDMS, needle size 24 ga, for use with autosampler

57329-U

Supelco

SPME fiber assembly Divinylbenzene/Carboxen/Polydimethylsiloxane (DVB/CAR/PDMS), needle size 24 ga, StableFlex, for use with autosampler

57304

Supelco

SPME fiber assembly polyacrylate (PA), d_f 85 μm(PA, for use with manual holder, needle size 24 ga

57291-U

Supelco

SPME fiber assembly Polydimethylsiloxane (PDMS), d_f 7 μm(PDMS, needle size 23 ga, for use with autosampler

469319

Sigma-Aldrich

Poly(dimethylsiloxane), viscosity 1.0 cSt (25 °C)

57906-U

Supelco

SPME fiber assembly Carboxen/Polydimethylsiloxane (CAR/PDMS), d_f 85 μm(CAR/PDMS, for use with autosampler, needle size 23 ga, metal alloy fiber

57912-U

Supelco

SPME fiber assembly Divinylbenzene/Carboxen/Polydimethylsiloxane (DVB/CAR/PDMS), for use with autosampler, needle size 23 ga, metal alloy fiber, fiber L 1 cm

57928-U

Supelco

SPME fiber assembly Polydimethylsiloxane (PDMS), metal alloy fiber, d_f 100 μm(PDMS, needle size 23 ga, for use with autosampler

57354-U

Supelco

SPME fiber assembly, Carbowax-Polyethylene Glycol (PEG) Coating, needle size 23 ga, d_f 60 μm(PEG, for use with autosampler

57439-U

Supelco

SPME-OC Fiber Assembly, Polydimethylsiloxane/Divinylbenzene (PDMS/DVB), d_f 75 μm(Coating thickness includes 65 μm coating + 10 μm OC (overcoating), needle size 23 ga, pkg of 3 ea, fiber L 1 cm

57359-U

Supelco

SPME Portable Field Sampler, coating PDMS/DVB

57294-U

Supelco

SPME fiber assembly polyacrylate (PA), d_f 85 μm(PA, for use with autosampler, needle size 23 ga

57335-U

Supelco

SPME fiber assembly Carboxen/Polydimethylsiloxane (CAR/PDMS), d_f 85 μm(CAR/PDMS, needle size 24 ga, StableFlex, for use with autosampler

57342-U

Supelco

SPME fiber assembly Polydimethylsiloxane (PDMS), d_f 100 μm(PDMS, for use with manual holder, needle size 23 ga

57343-U

Supelco

SPME fiber assembly Carboxen/Polydimethylsiloxane (CAR/PDMS), d_f 75 μm(CAR/PDMS, needle size 23 ga, for use with autosampler

57298-U

Supelco

SPME fiber assembly Divinylbenzene/Carboxen/Polydimethylsiloxane (DVB/CAR/PDMS), needle size 23 ga, StableFlex, for use with autosampler

57295-U

Supelco

SPME fiber assembly Carboxen/Polydimethylsiloxane (CAR/PDMS), d_f 85 μm(CAR/PDMS, needle size 23 ga, StableFlex, for use with autosampler