Skip to Content
Merck
All Photos(3)

Key Documents

View All Documentation

N144

Sigma-Aldrich

Nitrendipine

>95%, powder

Synonym(s):

1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid ethyl methyl ester

Sign Into View Organizational & Contract Pricing
All Photos(3)

About This Item

Empirical Formula (Hill Notation):
C18H20N2O6
CAS Number:
39562-70-4
Molecular Weight:
360.36
EC Number:
254-513-1
MDL number:
MFCD00082255
UNSPSC Code:
12352200
PubChem Substance ID:
24277857
NACRES:
NA.77

Assay

>95%

form

powder

color

yellow to green

solubility

methanol: 15 mg/mL
DMSO: 17.5 mg/mL
H2O: insoluble

SMILES string

CCOC(=O)C1=C(C)NC(C)=C(C1c2cccc(c2)[N+]([O-])=O)C(=O)OC

InChI

1S/C18H20N2O6/c1-5-26-18(22)15-11(3)19-10(2)14(17(21)25-4)16(15)12-7-6-8-13(9-12)20(23)24/h6-9,16,19H,5H2,1-4H3

InChI key

PVHUJELLJLJGLN-UHFFFAOYSA-N

Gene Information

human ... ADORA3(140) , CACNG1(786) , KCNH1(3756) , TTR(7276)
rat ... Adora1(29290) , Adora2a(25369)

Looking for similar products? Visit Product Comparison Guide

Biochem/physiol Actions

Ca2+ channel blocker; anti-hypertensive.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Felix Steger et al.
Radiation oncology (London, England), 7, 212-212 (2012-12-18)
5-Fluorouracil (5-FU) is an antimetabolite, which is frequently used as chemotherapeutic agent for combined chemoradiotherapy. The purpose of this study was to present the clinical course of three patients who developed severe cardiac toxicity by 5-FU and to give a
Annik Bergeron et al.
Bioanalysis, 4(8), 897-908 (2012-04-27)
In the past several years, the impact of changing counter ions while keeping the same anticoagulant in bioanalytical LC-MS/MS methods has become a highly discussed topic. In order to confirm that there is no impact from counter ions, matrix effect
Jian X Wu et al.
International journal of pharmaceutics, 433(1-2), 60-70 (2012-05-09)
This study focuses on the development of an automated image analysis method to extract information on nucleation and crystal growth from polarized light micrographs. Using the developed image analysis method, four parameters related to nucleation and crystal growth could be
Peng Quan et al.
AAPS PharmSciTech, 12(4), 1136-1143 (2011-09-06)
The present investigation was undertaken with the objective of developing a solid formulation containing nitrendipine nanocrystals for oral delivery. Nitrendipine nanocrystals were prepared using a tandem precipitation-homogenization process. Then, spray drying, a cost-effective method very popular in industrial situations, was
Dengning Xia et al.
Pharmaceutical research, 29(1), 158-169 (2011-07-13)
To investigate anti-solvent crystallization and growth mechanism of nitrendipine spherical crystals in an aqueous solution containing polymeric additives. Size and shape of crystals were investigated using laser diffractometry, optical microscopy and scanning electron microscopy (SEM). Crystalline form was determined by
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service