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Y0001377

Nitrofural for peak identification

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

5-Nitro-2-furaldehyde semicarbazone, 5-Nitro-2-furfural semicarbazone, Furacin, NFZ, Nitrofurazone

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About This Item

Empirical Formula (Hill Notation):
C6H6N4O4
CAS Number:
59-87-0
Molecular Weight:
198.14
Beilstein:
86403
MDL number:
MFCD00003225
UNSPSC Code:
41116107
PubChem Substance ID:
329831391
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

nitrofural

manufacturer/tradename

EDQM

mp

242-244 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

NC(=O)N\N=C\c1ccc(o1)[N+]([O-])=O

InChI

1S/C6H6N4O4/c7-6(11)9-8-3-4-1-2-5(14-4)10(12)13/h1-3H,(H3,7,9,11)/b8-3+

InChI key

IAIWVQXQOWNYOU-FPYGCLRLSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Nitrofural for peak identification EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Muta. 2 - Repr. 2 - Skin Sens. 1 - STOT RE 2

Target Organs

male reproductive organs

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

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Effect of nitrofurans and NO generators on biofilm formation by Pseudomonas aeruginosa PAO1 and Burkholderia cenocepacia 370.
Zaitseva J, et al.
Research in Microbiology, 160(5), 353-357 (2009)
Teresa del Castillo et al.
ChemMedChem, 9(2), 383-389 (2013-12-18)
Cyclodextrins have been conjugated to target various receptors and have also been functionalized with carbohydrates for targeting specific organs. However, this approach is based on a rigid design that implies the ad hoc synthesis of each cyclodextrin-targeting agent conjugate. We
Characterization of the genotoxic properties of nitrofurans: nitrofurazone and furazolidone.
M Kobierska-Szeliga et al.
Acta biochimica Polonica, 41(1), 1-5 (1994-01-01)
Ahmet Pişkin et al.
The Journal of dermatological treatment, 25(4), 350-357 (2012-07-21)
Momordica charantia (MC; bitter gourd) is a traditional herbal commonly used for its antidiabetic, antioxidant, contraceptive and antibacterial properties. In the current study, the authors aim to observe the topical effect of MC cream on the wound-healing process in rabbits.
[Therapeutically used 5-nitrofural derivatives. Review of literature. 2].
H Kala et al.
Die Pharmazie, 26(4), 193-207 (1971-04-01)
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