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100403X

Avanti

GPC-d9

Avanti Research™ - A Croda Brand

Synonym(s):

(d9)choline alfoscerate
α-GPC(d9); α-GPC(d9)

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About This Item

Empirical Formula (Hill Notation):
C8H11D9NO6P
CAS Number:
2260669-07-4
Molecular Weight:
266.28
UNSPSC Code:
51321705
NACRES:
NA.25

description

L-α-glycerophosphoryl(choline-d9), water:ethanol (9:1)

Assay

>99% phosphorus (P) basis (qNMR)

form

solution

packaging

pkg of 1 × 1 mL (100403X-100ug)

manufacturer/tradename

Avanti Research™ - A Croda Brand

concentration

0.1 mg/mL (100403X-100ug)

shipped in

dry ice

storage temp.

−20°C

General description

GPC rapidly delivers choline to the brain across the blood–brain barrier and is a biosynthetic precursor of the acetylcholine neurotransmitter.
Glycerophosphocholine (GPC), is a water-soluble deacylated phosphatidylcholine derivative. It is majorly generated from choline based phospholipids associated with membranes. GPC is widely distributed in human blood and saliva. L-α-glycerophosphoryl(choline-d9) (GPC-d9) is the deuterium-labeled form of GPC.

Application

GPC-d9 has been used as an internal standard in ultra-performance liquid chromatograph coupled to a SCIEX 4500QT mass spectrometer (UPLC-MS/MS) for the quantification of choline compounds from whole milk samples.

Biochem/physiol Actions

Glycerophosphocholine (GPC) protects mitochondrial respiratory complex I during oxidative stress associated with liver ischemia-reperfusion. GPC is an ergogenic supplement that improves muscle force production. The deuterium-labeled glycerophosphocholine is employed as an internal standard for human milk choline quantification using liquid chromatography-tandem mass spectrometry.

Packaging

5 mL Clear Glass Sealed Ampule (100403X-100ug)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Phosphatidylcholine biosynthesis in Mitis group streptococci via host metabolite scavenging
Joyce LR, et al.
Journal of Bacteriology, 201(22), e00495-e00419 (2019)
Targeting mitochondrial dysfunction with L-alpha glycerylphosphorylcholine
Strifler G, et al.
Testing, 11(11) (2016)
Total Water-Soluble Choline Concentration Does Not Differ in Milk from Vegan, Vegetarian, and Nonvegetarian Lactating Women
Perrin MT, et al.
The Journal of Nutrition, 11(12), 3024-3024 (2019)
Evaluation of the effects of two doses of alpha glycerylphosphorylcholine on physical and psychomotor performance
Marcus L, et al.
Journal of the International Society of Sports Nutrition, 14(1), 39-39 (2017)
Variability of Water-Soluble Forms of Choline Concentrations in Human Milk during Storage, after Pasteurization, and among Women
Moukarzel S, et al.
Nutrients, 11(12), 3024-3024 (2019)
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