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P4153

Sigma-Aldrich

Prednisolone 21-hemisuccinate sodium salt

≥90%, powder

Sinónimos:

Δ1-Hydrocortisone 21-hemisuccinate, 1,4-Pregnadiene-11β,17,21-triol-3,20-dione 21-hemisuccinate, 11β,17α,21-Trihydroxy-1,4-pregnadiene-3,20-dione 21-hemisuccinate

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About This Item

Fórmula lineal:
C25H31O8Na
Número de CAS:
1715-33-9
Peso molecular:
482.50
EC Number:
216-995-1
MDL number:
MFCD00070045
UNSPSC Code:
51111800
PubChem Substance ID:
24898507
NACRES:
NA.77

biological source

synthetic

sterility

non-sterile

assay

≥90%

form

powder

color

white

solubility

water: 50 mg/mL, clear, colorless

shipped in

ambient

storage temp.

−20°C

SMILES string

[Na].[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(=O)COC(=O)CCC(O)=O

InChI

1S/C25H32O8.Na.H/c1-23-9-7-15(26)11-14(23)3-4-16-17-8-10-25(32,24(17,2)12-18(27)22(16)23)19(28)13-33-21(31)6-5-20(29)30;;/h7,9,11,16-18,22,27,32H,3-6,8,10,12-13H2,1-2H3,(H,29,30);;/t16-,17-,18-,22+,23-,24-,25-;;/m0../s1

InChI key

HLHQSPQPHMOTMP-FKIWUUNWSA-N

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pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H360D

Hazard Classifications

Repr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

Certificados de análisis (COA)

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Sigma-Aldrich

D4902

Dexametasona

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American journal of ophthalmology, 143(1), 176-178 (2006-12-26)
To evaluate the six-month results of patients treated with intravitreal prednisolone sodium succinate injections for persistent diabetic macular edema. Retrospective, noncontrolled, clinical case series. Nineteen eyes had intravitreal injections with prednisolone sodium succinate. Need for retreatment was based on fluorescein
Toru Ohashi et al.
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Abnormal action potential (AP) recovery from adaptation was manifested as increased recovery (iR) or decreased recovery (dR) relative to the normal recovery range. dR was not analyzed statistically due to the very small number of cases. iR is considered an
Tomofumi Ogoshi et al.
Modern rheumatology, 18(6), 552-561 (2008-07-24)
The influence of glucocorticoid (GC) on bone in rats at different ages was investigated in order to provide insight into human glucocorticoid induced osteoporosis (GCOP). Three-, 6-, and 12-month-old female Wistar rats were divided into four groups: Zero-time control (ZT)
E Mabuchi et al.
The British journal of dermatology, 157(3), 596-598 (2007-06-29)
Non-Herlitz junctional epidermolysis bullosa (JEB-nH), a nonlethal variant of junctional epidermolysis bullosa (JEB), is an autosomal recessive disorder characterized by separation of the dermal-epidermal junction. JEB-nH is caused by mutations in several genes and lack of the COL17A1 gene product
Mareike Probst et al.
International journal of pharmaceutics, 532(1), 519-527 (2017-09-25)
The number of intramuscularly applied dosage forms has been continuously increasing during the last decades. However, up to date no in vitro dissolution test method for parenteral dosage forms has been described in the Ph. Eur. or USP. It was
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