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P2508

Sigma-Aldrich

Proflavine hemisulfate salt hydrate

powder

Sinónimos:

3,6-Diaminoacridine hemisulfate salt

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About This Item

Fórmula empírica (notación de Hill):
C13H11N3 · 0.5 H2SO4 · xH2O
Número de CAS:
1811-28-5
Peso molecular:
258.29 (anhydrous basis)
Beilstein/REAXYS Number:
3921806
EC Number:
217-320-3
MDL number:
MFCD00149650
UNSPSC Code:
12171500
PubChem Substance ID:
24898329
NACRES:
NA.47

form

powder

solubility

H2O: 10 mg/mL

fluorescence

λex 444 nm; λem 508 nm (0.01M HCl)

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

[H]O[H].OS(O)(=O)=O.Nc1ccc2cc3ccc(N)cc3nc2c1.Nc4ccc5cc6ccc(N)cc6nc5c4

InChI

1S/2C13H11N3.H2O4S.H2O/c2*14-10-3-1-8-5-9-2-4-11(15)7-13(9)16-12(8)6-10;1-5(2,3)4;/h2*1-7H,14-15H2;(H2,1,2,3,4);1H2

InChI key

DTRLDKDFCPUGCA-UHFFFAOYSA-N

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General description

Proflavine is a small, amphipathic, acridine-derived fluorescent dye.Proflavine hemisulfate is used as a rapid stain for cytological studies of biological specimens. It stains cytoplasmic structures and nuclei. Proflavine has the capability to intercalate double stranded DNA.

Application

Proflavine hemisulfate salt hydrate has been used to stain cells of the 1483 cell line. It has also been used as a calibrating dye in fluorescence resonance energy transfer (FRET) analysis.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

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PLoS ONE, 10(5) (2015)
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