Saltar al contenido
Merck
Todas las fotos(4)

Key Documents

View All Documentation

239283

Sigma-Aldrich

Potassium hydrogenfluoride

99%

Sinónimos:

Potassium bifluoride, Potassium hydrogen difluoride

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
Todas las fotos(4)

About This Item

Fórmula lineal:
KHF2
Número de CAS:
7789-29-9
Peso molecular:
78.10
EC Number:
232-156-2
MDL number:
MFCD00011403
UNSPSC Code:
12352300
PubChem Substance ID:
329752525
NACRES:
NA.55

Quality Level

100

assay

99%

form

lumps
powder or crystals

mp

239 °C (lit.)

density

2.37 g/mL at 25 °C (lit.)

SMILES string

[F-].[K+].F[H]

InChI

1S/2FH.K/h2*1H;/q;;+1/p-1

InChI key

VBKNTGMWIPUCRF-UHFFFAOYSA-M

¿Está buscando productos similares? Visita Guía de comparación de productos

Application

  • Synthesis of 4′-deoxy-4′-fluorokanamycin A and B: This study discusses the synthetic applications of Potassium hydrogenfluoride in the development of fluorinated antibiotics, highlighting its role in selective fluorination processes (Takahashi Y et al., 1992).
  • Reaction of 2-deoxy-6-O-[2,3-dideoxy-4,6-O-isopropylidene-2,3-(N-tosylepimino)-alpha-D-mannopyranosyl]-4,5-O-isopropylidene-1,3-di-N-tosylstreptamine with potassium hydrogenfluoride: This article explores the chemical behavior of Potassium hydrogenfluoride under specific synthetic conditions, providing insights into its role in complex organic transformations (Kobayashi Y et al., 1992).
  • A synthetic study of methyl 3-deoxy-3-fluoro-alpha-D-glucopyranosides from methyl 2,3-anhydro-alpha-D-allopyranosides, and synthesis of 3′-deoxy-3′-fluorokanamycin A and 3′-chloro-3′-deoxykanamycin A: This research delves into the synthesis of modified sugars using Potassium hydrogenfluoride, illustrating its utility in the creation of novel glycoside structures, which are important in drug development (Umemura E et al., 1992).

pictograms

Skull and crossbonesCorrosion
GHS06,GHS05

signalword

Danger

hcodes

H301,H314

Hazard Classifications

Acute Tox. 3 Oral - Eye Dam. 1 - Skin Corr. 1B

Storage Class

6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Potassium Hydrogen Fluoride.
Molander GA, et al.
e-EROS Encyclopedia of Reagents for Organic Synthesis. (2012)
Reaction of 2-deoxy-6-O-[2,3-dideoxy-4,6-O-isopropylidene-2,3- (N-tosylepimino)-alpha-D-mannopyranosyl]-4,5-O-isopropylidene-1,3-di-N- tosylstreptamine with potassium hydrogenfluoride.
Y Kobayashi et al.
Carbohydrate research, 229(2), 363-368 (1992-05-22)
Gary A Molander et al.
The Journal of organic chemistry, 73(17), 6841-6844 (2008-08-07)
A number of alkynyl pinacolboronates bearing various functional groups were synthesized according to literature methods. These were then stereoselectively reduced to the cis-alkenyl pinacolboronates via hydroboration with dicyclohexylborane followed by chemoselective protodeboronation using acetic acid. Treatment with potassium hydrogen fluoride
Zhibo Liu et al.
Nature protocols, 10(9), 1423-1432 (2015-08-28)
Herein we present a general protocol for the functionalization of biomolecules with an organotrifluoroborate moiety so that they can be radiolabeled with aqueous (18)F fluoride ((18)F(-)) and used for positron emission tomography (PET) imaging. Among the β(+)-emitting radionuclides, fluorine-18 ((18)F)
Matthew J Hesse et al.
Angewandte Chemie (International ed. in English), 51(50), 12444-12448 (2012-11-07)
E-allylic boronic esters undergo a highly diastereoselective protodeboronation with TBAF⋅3 H(2)O to give Z-trisubstituted alkenes. The selectivity can be switched to give predominantly the E-alkene instead by using KHF(2)/TsOH (see scheme). The utility of the methodology has been illustrated in a

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico